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Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model.
Proud PC, Tsitoura D, Watson RJ, Chua BY, Aram MJ, Bewley KR, Cavell BE, Cobb R, Dowall S, Fotheringham SA, Ho CMK, Lucas V, Ngabo D, Rayner E, Ryan KA, Slack GS, Thomas S, Wand NI, Yeates P, Demaison C, Zeng W, Holmes I, Jackson DC, Bartlett NW, Mercuri F, Carroll MW. Proud PC, et al. Among authors: carroll mw. EBioMedicine. 2021 Jan;63:103153. doi: 10.1016/j.ebiom.2020.103153. Epub 2020 Dec 3. EBioMedicine. 2021. PMID: 33279857 Free PMC article.
Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir.
Marriott AC, Dove BK, Whittaker CJ, Bruce C, Ryan KA, Bean TJ, Rayner E, Pearson G, Taylor I, Dowall S, Plank J, Newman E, Barclay WS, Dimmock NJ, Easton AJ, Hallis B, Silman NJ, Carroll MW. Marriott AC, et al. Among authors: carroll mw. PLoS One. 2014 Apr 7;9(4):e94090. doi: 10.1371/journal.pone.0094090. eCollection 2014. PLoS One. 2014. PMID: 24709834 Free PMC article.
Development of a Cost-effective Ovine Polyclonal Antibody-Based Product, EBOTAb, to Treat Ebola Virus Infection.
Dowall SD, Callan J, Zeltina A, Al-Abdulla I, Strecker T, Fehling SK, Krähling V, Bosworth A, Rayner E, Taylor I, Charlton S, Landon J, Cameron I, Hewson R, Nasidi A, Bowden TA, Carroll MW. Dowall SD, et al. Among authors: carroll mw. J Infect Dis. 2016 Apr 1;213(7):1124-33. doi: 10.1093/infdis/jiv565. Epub 2015 Dec 28. J Infect Dis. 2016. PMID: 26715676 Free PMC article.
Influenza A Virus Challenge Models in Cynomolgus Macaques Using the Authentic Inhaled Aerosol and Intra-Nasal Routes of Infection.
Marriott AC, Dennis M, Kane JA, Gooch KE, Hatch G, Sharpe S, Prevosto C, Leeming G, Zekeng EG, Staples KJ, Hall G, Ryan KA, Bate S, Moyo N, Whittaker CJ, Hallis B, Silman NJ, Lalvani A, Wilkinson TM, Hiscox JA, Stewart JP, Carroll MW. Marriott AC, et al. Among authors: carroll mw. PLoS One. 2016 Jun 16;11(6):e0157887. doi: 10.1371/journal.pone.0157887. eCollection 2016. PLoS One. 2016. PMID: 27311020 Free PMC article.
245 results