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Cohesin mutations are synthetic lethal with stimulation of WNT signaling.
Chin CV, Antony J, Ketharnathan S, Labudina A, Gimenez G, Parsons KM, He J, George AJ, Pallotta MM, Musio A, Braithwaite A, Guilford P, Hannan RD, Horsfield JA. Chin CV, et al. Among authors: gimenez g. Elife. 2020 Dec 7;9:e61405. doi: 10.7554/eLife.61405. Elife. 2020. PMID: 33284104 Free PMC article.
The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer.
Kazantseva M, Mehta S, Eiholzer RA, Gimenez G, Bowie S, Campbell H, Reily-Bell AL, Roth I, Ray S, Drummond CJ, Reid G, Joruiz SM, Wiles A, Morrin HR, Reader KL, Hung NA, Baird MA, Slatter TL, Braithwaite AW. Kazantseva M, et al. Among authors: gimenez g. Cell Death Dis. 2019 Aug 20;10(9):631. doi: 10.1038/s41419-019-1861-1. Cell Death Dis. 2019. PMID: 31431617 Free PMC article.
Innate immune checkpoint inhibitor resistance is associated with melanoma sub-types exhibiting invasive and de-differentiated gene expression signatures.
Hossain SM, Gimenez G, Stockwell PA, Tsai P, Print CG, Rys J, Cybulska-Stopa B, Ratajska M, Harazin-Lechowska A, Almomani S, Jackson C, Chatterjee A, Eccles MR. Hossain SM, et al. Among authors: gimenez g. Front Immunol. 2022 Sep 28;13:955063. doi: 10.3389/fimmu.2022.955063. eCollection 2022. Front Immunol. 2022. PMID: 36248850 Free PMC article.
182 results