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328 results

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Page 1
Nebulised surfactant for the treatment of severe COVID-19 in adults (COV-Surf): A structured summary of a study protocol for a randomized controlled trial.
Dushianthan A, Clark H, Madsen J, Mogg R, Matthews L, Berry L, de la Serna JB, Batchelor J, Brealey D, Hussell T, Porter J, Djukanovic R, Feelisch M, Postle A, Grocott MPW. Dushianthan A, et al. Among authors: djukanovic r. Trials. 2020 Dec 10;21(1):1014. doi: 10.1186/s13063-020-04944-5. Trials. 2020. PMID: 33302976 Free PMC article. Clinical Trial.
A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial.
Hanratty CE, Matthews JG, Arron JR, Choy DF, Pavord ID, Bradding P, Brightling CE, Chaudhuri R, Cowan DC, Djukanovic R, Gallagher N, Fowler SJ, Hardman TC, Harrison T, Holweg CT, Howarth PH, Lordan J, Mansur AH, Menzies-Gow A, Mosesova S, Niven RM, Robinson DS, Shaw DE, Walker S, Woodcock A, Heaney LG; RASP-UK (Refractory Asthma Stratification Programme) Consortium. Hanratty CE, et al. Among authors: djukanovic r. Trials. 2018 Jan 4;19(1):5. doi: 10.1186/s13063-017-2384-7. Trials. 2018. PMID: 29301585 Free PMC article.
Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19.
Mann ER, Menon M, Knight SB, Konkel JE, Jagger C, Shaw TN, Krishnan S, Rattray M, Ustianowski A, Bakerly ND, Dark P, Lord G, Simpson A, Felton T, Ho LP; NIHR Respiratory TRC,; Feldmann M; CIRCO,; Grainger JR, Hussell T. Mann ER, et al. Sci Immunol. 2020 Sep 17;5(51):eabd6197. doi: 10.1126/sciimmunol.abd6197. Sci Immunol. 2020. PMID: 32943497 Free PMC article.
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial.
Monk PD, Marsden RJ, Tear VJ, Brookes J, Batten TN, Mankowski M, Gabbay FJ, Davies DE, Holgate ST, Ho LP, Clark T, Djukanovic R, Wilkinson TMA; Inhaled Interferon Beta COVID-19 Study Group. Monk PD, et al. Among authors: djukanovic r. Lancet Respir Med. 2021 Feb;9(2):196-206. doi: 10.1016/S2213-2600(20)30511-7. Epub 2020 Nov 12. Lancet Respir Med. 2021. PMID: 33189161 Free PMC article. Clinical Trial.
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB, Lone NI, Leavy OC, Daines L, Baillie JK, Brown JS, Chalder T, De Soyza A, Diar Bakerly N, Easom N, Geddes JR, Greening NJ, Hart N, Heaney LG, Heller S, Howard L, Hurst JR, Jacob J, Jenkins RG, Jolley C, Kerr S, Kon OM, Lewis K, Lord JM, McCann GP, Neubauer S, Openshaw PJM, Parekh D, Pfeffer P, Rahman NM, Raman B, Richardson M, Rowland M, Semple MG, Shah AM, Singh SJ, Sheikh A, Thomas D, Toshner M, Chalmers JD, Ho LP, Horsley A, Marks M, Poinasamy K, Wain LV, Brightling CE; PHOSP-COVID Collaborative Group. Evans RA, et al. Lancet Respir Med. 2021 Nov;9(11):1275-1287. doi: 10.1016/S2213-2600(21)00383-0. Epub 2021 Oct 7. Lancet Respir Med. 2021. PMID: 34627560 Free PMC article.
Rapid Phospholipid Turnover after Surfactant Nebulization in Severe COVID-19 Infection: A Randomized Clinical Trial.
Postle AD, Clark HW, Fink J, Madsen J, Koster G, Panchal M, Djukanovic R, Brealey D, Grocott MPW, Dushianthan A. Postle AD, et al. Among authors: djukanovic r. Am J Respir Crit Care Med. 2022 Feb 15;205(4):471-473. doi: 10.1164/rccm.202110-2279LE. Am J Respir Crit Care Med. 2022. PMID: 34874818 Free PMC article. Clinical Trial. No abstract available.
Large scale clinical trials: lessons from the COVID-19 pandemic.
Horsley AR, Pearmain L, Knight S, Schindler N, Wang R, Bennett M, Robey RC, Davies JC, Djukanović R, Heaney LG, Hussell T, Marciniak SJ, McGarvey LP, Porter J, Wilkinson T, Brightling C, Ho LP. Horsley AR, et al. Among authors: djukanovic r. BMJ Open Respir Res. 2022 Jun;9(1):e001226. doi: 10.1136/bmjresp-2022-001226. BMJ Open Respir Res. 2022. PMID: 35701071 Free PMC article.
Early-phase clinical trials in a pandemic: learning from the response to COVID-19.
Horsley A, Brightling C, Davies J, Djukanovic R, Heaney LG, Hussell T, Marciniak SJ, McGarvey L, Porter JC, Wilkinson T, Ho LP; NIHR Respiratory Translational Research Collaboration network. Horsley A, et al. Among authors: djukanovic r. Lancet Respir Med. 2022 Jul;10(7):625-627. doi: 10.1016/S2213-2600(22)00062-5. Epub 2022 Jun 13. Lancet Respir Med. 2022. PMID: 35709826 Free PMC article. No abstract available.
328 results