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Nebulised surfactant for the treatment of severe COVID-19 in adults (COV-Surf): A structured summary of a study protocol for a randomized controlled trial.
Dushianthan A, Clark H, Madsen J, Mogg R, Matthews L, Berry L, de la Serna JB, Batchelor J, Brealey D, Hussell T, Porter J, Djukanovic R, Feelisch M, Postle A, Grocott MPW. Dushianthan A, et al. Among authors: hussell t. Trials. 2020 Dec 10;21(1):1014. doi: 10.1186/s13063-020-04944-5. Trials. 2020. PMID: 33302976 Free PMC article. Clinical Trial.
Early-phase clinical trials in a pandemic: learning from the response to COVID-19.
Horsley A, Brightling C, Davies J, Djukanovic R, Heaney LG, Hussell T, Marciniak SJ, McGarvey L, Porter JC, Wilkinson T, Ho LP; NIHR Respiratory Translational Research Collaboration network. Horsley A, et al. Among authors: hussell t. Lancet Respir Med. 2022 Jul;10(7):625-627. doi: 10.1016/S2213-2600(22)00062-5. Epub 2022 Jun 13. Lancet Respir Med. 2022. PMID: 35709826 Free PMC article. No abstract available.
Large scale clinical trials: lessons from the COVID-19 pandemic.
Horsley AR, Pearmain L, Knight S, Schindler N, Wang R, Bennett M, Robey RC, Davies JC, Djukanović R, Heaney LG, Hussell T, Marciniak SJ, McGarvey LP, Porter J, Wilkinson T, Brightling C, Ho LP. Horsley AR, et al. Among authors: hussell t. BMJ Open Respir Res. 2022 Jun;9(1):e001226. doi: 10.1136/bmjresp-2022-001226. BMJ Open Respir Res. 2022. PMID: 35701071 Free PMC article.
Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19.
Mann ER, Menon M, Knight SB, Konkel JE, Jagger C, Shaw TN, Krishnan S, Rattray M, Ustianowski A, Bakerly ND, Dark P, Lord G, Simpson A, Felton T, Ho LP; NIHR Respiratory TRC,; Feldmann M; CIRCO,; Grainger JR, Hussell T. Mann ER, et al. Among authors: hussell t. Sci Immunol. 2020 Sep 17;5(51):eabd6197. doi: 10.1126/sciimmunol.abd6197. Sci Immunol. 2020. PMID: 32943497 Free PMC article.
The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation.
Svedberg FR, Brown SL, Krauss MZ, Campbell L, Sharpe C, Clausen M, Howell GJ, Clark H, Madsen J, Evans CM, Sutherland TE, Ivens AC, Thornton DJ, Grencis RK, Hussell T, Cunoosamy DM, Cook PC, MacDonald AS. Svedberg FR, et al. Among authors: hussell t. Nat Immunol. 2019 May;20(5):571-580. doi: 10.1038/s41590-019-0352-y. Epub 2019 Apr 1. Nat Immunol. 2019. PMID: 30936493 Free PMC article.
Alterations in T and B cell function persist in convalescent COVID-19 patients.
Shuwa HA, Shaw TN, Knight SB, Wemyss K, McClure FA, Pearmain L, Prise I, Jagger C, Morgan DJ, Khan S, Brand O, Mann ER, Ustianowski A, Bakerly ND, Dark P, Brightling CE, Brij S; CIRCO; Felton T, Simpson A, Grainger JR, Hussell T, Konkel JE, Menon M. Shuwa HA, et al. Among authors: hussell t. Med. 2021 Jun 11;2(6):720-735.e4. doi: 10.1016/j.medj.2021.03.013. Epub 2021 Mar 31. Med. 2021. PMID: 33821250 Free PMC article.
COVID-19 therapeutics: Challenges and directions for the future.
Robinson PC, Liew DFL, Tanner HL, Grainger JR, Dwek RA, Reisler RB, Steinman L, Feldmann M, Ho LP, Hussell T, Moss P, Richards D, Zitzmann N. Robinson PC, et al. Among authors: hussell t. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2119893119. doi: 10.1073/pnas.2119893119. Epub 2022 Apr 6. Proc Natl Acad Sci U S A. 2022. PMID: 35385354 Free PMC article. Review.
Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed.
Feldmann M, Maini RN, Woody JN, Holgate ST, Winter G, Rowland M, Richards D, Hussell T. Feldmann M, et al. Among authors: hussell t. Lancet. 2020 May 2;395(10234):1407-1409. doi: 10.1016/S0140-6736(20)30858-8. Epub 2020 Apr 9. Lancet. 2020. PMID: 32278362 Free PMC article. No abstract available.
171 results