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Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, Schneider-Luftman D, Herbert E, Stamp G, Brough R, Pettitt S, Lord CJ, West SC, Ahel I, Ahel D, Chapman JR, Deindl S, Boulton SJ. Hewitt G, et al. Among authors: ahel i, ahel d. Mol Cell. 2021 Feb 18;81(4):767-783.e11. doi: 10.1016/j.molcel.2020.12.006. Epub 2020 Dec 16. Mol Cell. 2021. PMID: 33333017 Free PMC article.
Actions of aprataxin in multiple DNA repair pathways.
Rass U, Ahel I, West SC. Rass U, et al. Among authors: ahel i. J Biol Chem. 2007 Mar 30;282(13):9469-9474. doi: 10.1074/jbc.M611489200. Epub 2007 Feb 2. J Biol Chem. 2007. PMID: 17276982 Free article.
Defective DNA repair and neurodegenerative disease.
Rass U, Ahel I, West SC. Rass U, et al. Among authors: ahel i. Cell. 2007 Sep 21;130(6):991-1004. doi: 10.1016/j.cell.2007.08.043. Cell. 2007. PMID: 17889645 Free article. Review.
DNA repair factor APLF is a histone chaperone.
Mehrotra PV, Ahel D, Ryan DP, Weston R, Wiechens N, Kraehenbuehl R, Owen-Hughes T, Ahel I. Mehrotra PV, et al. Among authors: ahel i, ahel d. Mol Cell. 2011 Jan 7;41(1):46-55. doi: 10.1016/j.molcel.2010.12.008. Mol Cell. 2011. PMID: 21211722 Free PMC article.
129 results