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Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
Mol Cell. 2021 Feb 18;81(4):767-783.e11. doi: 10.1016/j.molcel.2020.12.006. Epub 2020 Dec 16.
Mol Cell. 2021.
PMID: 33333017
Free PMC article.
RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions.
Kotsantis P, Segura-Bayona S, Margalef P, Marzec P, Ruis P, Hewitt G, Bellelli R, Patel H, Goldstone R, Poetsch AR, Boulton SJ.
Kotsantis P, et al. Among authors: ruis p.
Cell Rep. 2020 Dec 22;33(12):108546. doi: 10.1016/j.celrep.2020.108546.
Cell Rep. 2020.
PMID: 33357438
Free PMC article.
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The end protection problem-an unexpected twist in the tail.
Ruis P, Boulton SJ.
Ruis P, et al.
Genes Dev. 2021 Jan 1;35(1-2):1-21. doi: 10.1101/gad.344044.120. Epub 2020 Dec 23.
Genes Dev. 2021.
PMID: 33361389
Free PMC article.
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SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance.
Panier S, Maric M, Hewitt G, Mason-Osann E, Gali H, Dai A, Labadorf A, Guervilly JH, Ruis P, Segura-Bayona S, Belan O, Marzec P, Gaillard PL, Flynn RL, Boulton SJ.
Panier S, et al. Among authors: ruis p.
Mol Cell. 2019 Oct 3;76(1):27-43.e11. doi: 10.1016/j.molcel.2019.07.010. Epub 2019 Aug 22.
Mol Cell. 2019.
PMID: 31447390
Free PMC article.
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H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ.
Bayley R, Borel V, Moss RJ, Sweatman E, Ruis P, Ormrod A, Goula A, Mottram RMA, Stanage T, Hewitt G, Saponaro M, Stewart GS, Boulton SJ, Higgs MR.
Bayley R, et al. Among authors: ruis p.
Mol Cell. 2022 May 19;82(10):1924-1939.e10. doi: 10.1016/j.molcel.2022.03.030. Epub 2022 Apr 18.
Mol Cell. 2022.
PMID: 35439434
Free PMC article.
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CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle.
Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, Zheng XF, Flynn HR, Snijders AP, Chowdhury D, Cesare AJ, Boulton SJ.
Sarek G, et al. Among authors: ruis p.
Nature. 2019 Nov;575(7783):523-527. doi: 10.1038/s41586-019-1744-8. Epub 2019 Nov 13.
Nature. 2019.
PMID: 31723267
Free PMC article.
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TRF2-independent chromosome end protection during pluripotency.
Ruis P, Van Ly D, Borel V, Kafer GR, McCarthy A, Howell S, Blassberg R, Snijders AP, Briscoe J, Niakan KK, Marzec P, Cesare AJ, Boulton SJ.
Ruis P, et al.
Nature. 2021 Jan;589(7840):103-109. doi: 10.1038/s41586-020-2960-y. Epub 2020 Nov 25.
Nature. 2021.
PMID: 33239783
Free PMC article.
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General amino acid control in fission yeast is regulated by a nonconserved transcription factor, with functions analogous to Gcn4/Atf4.
Duncan CDS, Rodríguez-López M, Ruis P, Bähler J, Mata J.
Duncan CDS, et al. Among authors: ruis p.
Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1829-E1838. doi: 10.1073/pnas.1713991115. Epub 2018 Feb 5.
Proc Natl Acad Sci U S A. 2018.
PMID: 29432178
Free PMC article.
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