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Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors.
Hoffmann HH, Sánchez-Rivera FJ, Schneider WM, Luna JM, Soto-Feliciano YM, Ashbrook AW, Le Pen J, Leal AA, Ricardo-Lax I, Michailidis E, Hao Y, Stenzel AF, Peace A, Zuber J, Allis CD, Lowe SW, MacDonald MR, Poirier JT, Rice CM. Hoffmann HH, et al. Cell Host Microbe. 2021 Feb 10;29(2):267-280.e5. doi: 10.1016/j.chom.2020.12.009. Epub 2020 Dec 16. Cell Host Microbe. 2021. PMID: 33357464 Free PMC article.
Optimized base editors enable efficient editing in cells, organoids and mice.
Zafra MP, Schatoff EM, Katti A, Foronda M, Breinig M, Schweitzer AY, Simon A, Han T, Goswami S, Montgomery E, Thibado J, Kastenhuber ER, Sánchez-Rivera FJ, Shi J, Vakoc CR, Lowe SW, Tschaharganeh DF, Dow LE. Zafra MP, et al. Nat Biotechnol. 2018 Oct;36(9):888-893. doi: 10.1038/nbt.4194. Epub 2018 Jul 3. Nat Biotechnol. 2018. PMID: 29969439 Free PMC article.
NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination.
Ruscetti M, Leibold J, Bott MJ, Fennell M, Kulick A, Salgado NR, Chen CC, Ho YJ, Sanchez-Rivera FJ, Feucht J, Baslan T, Tian S, Chen HA, Romesser PB, Poirier JT, Rudin CM, de Stanchina E, Manchado E, Sherr CJ, Lowe SW. Ruscetti M, et al. Science. 2018 Dec 21;362(6421):1416-1422. doi: 10.1126/science.aas9090. Science. 2018. PMID: 30573629 Free PMC article.
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors.
Hoffmann HH, Schneider WM, Sánchez-Rivera FJ, Luna JM, Ashbrook AW, Soto-Feliciano YM, Leal AA, Le Pen J, Ricardo-Lax I, Michailidis E, Hao Y, Stenzel AF, Peace A, Allis CD, Lowe SW, MacDonald MR, Poirier JT, Rice CM. Hoffmann HH, et al. bioRxiv [Preprint]. 2020 Sep 11:2020.09.11.291716. doi: 10.1101/2020.09.11.291716. bioRxiv. 2020. PMID: 32935098 Free PMC article. Updated. Preprint.
Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks.
Schneider WM, Luna JM, Hoffmann HH, Sánchez-Rivera FJ, Leal AA, Ashbrook AW, Le Pen J, Michailidis E, Ricardo-Lax I, Peace A, Stenzel AF, Lowe SW, MacDonald MR, Rice CM, Poirier JT. Schneider WM, et al. bioRxiv [Preprint]. 2020 Oct 8:2020.10.07.326462. doi: 10.1101/2020.10.07.326462. bioRxiv. 2020. PMID: 33052332 Free PMC article. Updated. Preprint.
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks.
Schneider WM, Luna JM, Hoffmann HH, Sánchez-Rivera FJ, Leal AA, Ashbrook AW, Le Pen J, Ricardo-Lax I, Michailidis E, Peace A, Stenzel AF, Lowe SW, MacDonald MR, Rice CM, Poirier JT. Schneider WM, et al. Cell. 2021 Jan 7;184(1):120-132.e14. doi: 10.1016/j.cell.2020.12.006. Epub 2020 Dec 9. Cell. 2021. PMID: 33382968 Free PMC article.
Replication and single-cycle delivery of SARS-CoV-2 replicons.
Ricardo-Lax I, Luna JM, Thao TTN, Le Pen J, Yu Y, Hoffmann HH, Schneider WM, Razooky BS, Fernandez-Martinez J, Schmidt F, Weisblum Y, Trüeb BS, Berenguer Veiga I, Schmied K, Ebert N, Michailidis E, Peace A, Sánchez-Rivera FJ, Lowe SW, Rout MP, Hatziioannou T, Bieniasz PD, Poirier JT, MacDonald MR, Thiel V, Rice CM. Ricardo-Lax I, et al. Science. 2021 Nov 26;374(6571):1099-1106. doi: 10.1126/science.abj8430. Epub 2021 Oct 14. Science. 2021. PMID: 34648371 Free PMC article.
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
Sánchez-Rivera FJ, Diaz BJ, Kastenhuber ER, Schmidt H, Katti A, Kennedy M, Tem V, Ho YJ, Leibold J, Paffenholz SV, Barriga FM, Chu K, Goswami S, Wuest AN, Simon JM, Tsanov KM, Chakravarty D, Zhang H, Leslie CS, Lowe SW, Dow LE. Sánchez-Rivera FJ, et al. Nat Biotechnol. 2022 Jun;40(6):862-873. doi: 10.1038/s41587-021-01172-3. Epub 2022 Feb 14. Nat Biotechnol. 2022. PMID: 35165384 Free PMC article.
A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition.
Soto-Feliciano YM, Sánchez-Rivera FJ, Perner F, Barrows DW, Kastenhuber ER, Ho YJ, Carroll T, Xiong Y, Anand D, Soshnev AA, Gates L, Beytagh MC, Cheon D, Gu S, Liu XS, Krivtsov AV, Meneses M, de Stanchina E, Stone RM, Armstrong SA, Lowe SW, Allis CD. Soto-Feliciano YM, et al. Cancer Discov. 2023 Jan 9;13(1):146-169. doi: 10.1158/2159-8290.CD-22-0416. Cancer Discov. 2023. PMID: 36264143 Free PMC article.
49 results