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Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19.
Trump S, Lukassen S, Anker MS, Chua RL, Liebig J, Thürmann L, Corman VM, Binder M, Loske J, Klasa C, Krieger T, Hennig BP, Messingschlager M, Pott F, Kazmierski J, Twardziok S, Albrecht JP, Eils J, Hadzibegovic S, Lena A, Heidecker B, Bürgel T, Steinfeldt J, Goffinet C, Kurth F, Witzenrath M, Völker MT, Müller SD, Liebert UG, Ishaque N, Kaderali L, Sander LE, Drosten C, Laudi S, Eils R, Conrad C, Landmesser U, Lehmann I. Trump S, et al. Among authors: kaderali l. Nat Biotechnol. 2021 Jun;39(6):705-716. doi: 10.1038/s41587-020-00796-1. Epub 2020 Dec 24. Nat Biotechnol. 2021. PMID: 33361824
Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation.
Dirmeier S, Dächert C, van Hemert M, Tas A, Ogando NS, van Kuppeveld F, Bartenschlager R, Kaderali L, Binder M, Beerenwinkel N. Dirmeier S, et al. Among authors: kaderali l. PLoS Comput Biol. 2020 Feb 10;16(2):e1007587. doi: 10.1371/journal.pcbi.1007587. eCollection 2020 Feb. PLoS Comput Biol. 2020. PMID: 32040506 Free PMC article.
Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies.
Zitzmann C, Dächert C, Schmid B, van der Schaar H, van Hemert M, Perelson AS, van Kuppeveld FJM, Bartenschlager R, Binder M, Kaderali L. Zitzmann C, et al. Among authors: kaderali l. PLoS Comput Biol. 2023 Apr 4;19(4):e1010423. doi: 10.1371/journal.pcbi.1010423. eCollection 2023 Apr. PLoS Comput Biol. 2023. PMID: 37014904 Free PMC article.
148 results