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821 results

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Page 1
ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study.
Gill D, Arvanitis M, Carter P, Hernández Cordero AI, Jo B, Karhunen V, Larsson SC, Li X, Lockhart SM, Mason A, Pashos E, Saha A, Tan VY, Zuber V, Bossé Y, Fahle S, Hao K, Jiang T, Joubert P, Lunt AC, Ouwehand WH, Roberts DJ, Timens W, van den Berge M, Watkins NA, Battle A, Butterworth AS, Danesh J, Di Angelantonio E, Engelhardt BE, Peters JE, Sin DD, Burgess S. Gill D, et al. Among authors: roberts dj. R Soc Open Sci. 2020 Nov 18;7(11):200958. doi: 10.1098/rsos.200958. eCollection 2020 Nov. R Soc Open Sci. 2020. PMID: 33391794 Free PMC article.
Effects of adiposity on the human plasma proteome: observational and Mendelian randomisation estimates.
Goudswaard LJ, Bell JA, Hughes DA, Corbin LJ, Walter K, Davey Smith G, Soranzo N, Danesh J, Di Angelantonio E, Ouwehand WH, Watkins NA, Roberts DJ, Butterworth AS, Hers I, Timpson NJ. Goudswaard LJ, et al. Among authors: roberts dj. Int J Obes (Lond). 2021 Oct;45(10):2221-2229. doi: 10.1038/s41366-021-00896-1. Epub 2021 Jul 5. Int J Obes (Lond). 2021. PMID: 34226637 Free PMC article.
Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases.
Ritchie SC, Lambert SA, Arnold M, Teo SM, Lim S, Scepanovic P, Marten J, Zahid S, Chaffin M, Liu Y, Abraham G, Ouwehand WH, Roberts DJ, Watkins NA, Drew BG, Calkin AC, Di Angelantonio E, Soranzo N, Burgess S, Chapman M, Kathiresan S, Khera AV, Danesh J, Butterworth AS, Inouye M. Ritchie SC, et al. Among authors: roberts dj. Nat Metab. 2021 Nov;3(11):1476-1483. doi: 10.1038/s42255-021-00478-5. Epub 2021 Nov 8. Nat Metab. 2021. PMID: 34750571 Free PMC article.
Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke.
Chen L, Peters JE, Prins B, Persyn E, Traylor M, Surendran P, Karthikeyan S, Yonova-Doing E, Di Angelantonio E, Roberts DJ, Watkins NA, Ouwehand WH, Danesh J, Lewis CM, Bronson PG, Markus HS, Burgess S, Butterworth AS, Howson JMM. Chen L, et al. Among authors: roberts dj. Nat Commun. 2022 Oct 17;13(1):6143. doi: 10.1038/s41467-022-33675-1. Nat Commun. 2022. PMID: 36253349 Free PMC article.
Genomic atlas of the human plasma proteome.
Sun BB, Maranville JC, Peters JE, Stacey D, Staley JR, Blackshaw J, Burgess S, Jiang T, Paige E, Surendran P, Oliver-Williams C, Kamat MA, Prins BP, Wilcox SK, Zimmerman ES, Chi A, Bansal N, Spain SL, Wood AM, Morrell NW, Bradley JR, Janjic N, Roberts DJ, Ouwehand WH, Todd JA, Soranzo N, Suhre K, Paul DS, Fox CS, Plenge RM, Danesh J, Runz H, Butterworth AS. Sun BB, et al. Among authors: roberts dj. Nature. 2018 Jun;558(7708):73-79. doi: 10.1038/s41586-018-0175-2. Epub 2018 Jun 6. Nature. 2018. PMID: 29875488 Free PMC article.
The influence of rare variants in circulating metabolic biomarkers.
Riveros-Mckay F, Oliver-Williams C, Karthikeyan S, Walter K, Kundu K, Ouwehand WH, Roberts D, Di Angelantonio E, Soranzo N, Danesh J; INTERVAL Study; Wheeler E, Zeggini E, Butterworth AS, Barroso I. Riveros-Mckay F, et al. PLoS Genet. 2020 Mar 9;16(3):e1008605. doi: 10.1371/journal.pgen.1008605. eCollection 2020 Mar. PLoS Genet. 2020. PMID: 32150548 Free PMC article.
Lessons from the INTERVAL study - Authors' reply.
Di Angelantonio E, Thompson SG, Kaptoge S, Roberts DJ, Danesh J. Di Angelantonio E, et al. Among authors: roberts dj. Lancet. 2018 Jun 30;391(10140):2606. doi: 10.1016/S0140-6736(18)30760-8. Lancet. 2018. PMID: 30070221 No abstract available.
Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study.
Matías-García PR, Wilson R, Guo Q, Zaghlool SB, Eales JM, Xu X, Charchar FJ, Dormer J, Maalmi H, Schlosser P, Elhadad MA, Nano J, Sharma S, Peters A, Fornoni A, Mook-Kanamori DO, Winkelmann J, Danesh J, Di Angelantonio E, Ouwehand WH, Watkins NA, Roberts DJ, Petrera A, Graumann J, Koenig W, Hveem K, Jonasson C, Köttgen A, Butterworth A, Prunotto M, Hauck SM, Herder C, Suhre K, Gieger C, Tomaszewski M, Teumer A, Waldenberger M; Human Kidney Tissue Resource. Matías-García PR, et al. Among authors: roberts dj. J Am Soc Nephrol. 2021 Jul;32(7):1747-1763. doi: 10.1681/ASN.2020071070. Epub 2021 Jun 16. J Am Soc Nephrol. 2021. PMID: 34135082 Free PMC article.
821 results