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Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry.
Ge J, Wang R, Ju B, Zhang Q, Sun J, Chen P, Zhang S, Tian Y, Shan S, Cheng L, Zhou B, Song S, Zhao J, Wang H, Shi X, Ding Q, Liu L, Zhao J, Zhang Z, Wang X, Zhang L. Ge J, et al. Among authors: chen p. Nat Commun. 2021 Jan 11;12(1):250. doi: 10.1038/s41467-020-20501-9. Nat Commun. 2021. PMID: 33431856 Free PMC article.
Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies.
Yan R, Wang R, Ju B, Yu J, Zhang Y, Liu N, Wang J, Zhang Q, Chen P, Zhou B, Li Y, Shen Y, Zhang S, Tian L, Guo Y, Xia L, Zhong X, Cheng L, Ge X, Zhao J, Wang HW, Wang X, Zhang Z, Zhang L, Zhou Q. Yan R, et al. Among authors: chen p. Cell Res. 2021 May;31(5):517-525. doi: 10.1038/s41422-021-00487-9. Epub 2021 Mar 17. Cell Res. 2021. PMID: 33731853 Free PMC article.
Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.
Wang R, Zhang Q, Ge J, Ren W, Zhang R, Lan J, Ju B, Su B, Yu F, Chen P, Liao H, Feng Y, Li X, Shi X, Zhang Z, Zhang F, Ding Q, Zhang T, Wang X, Zhang L. Wang R, et al. Among authors: chen p. Immunity. 2021 Jul 13;54(7):1611-1621.e5. doi: 10.1016/j.immuni.2021.06.003. Epub 2021 Jun 8. Immunity. 2021. PMID: 34166623 Free PMC article.
Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2.
Zhang Q, Ju B, Ge J, Chan JF, Cheng L, Wang R, Huang W, Fang M, Chen P, Zhou B, Song S, Shan S, Yan B, Zhang S, Ge X, Yu J, Zhao J, Wang H, Liu L, Lv Q, Fu L, Shi X, Yuen KY, Liu L, Wang Y, Chen Z, Zhang L, Wang X, Zhang Z. Zhang Q, et al. Among authors: chen z, chen p. Nat Commun. 2021 Jul 9;12(1):4210. doi: 10.1038/s41467-021-24514-w. Nat Commun. 2021. PMID: 34244522 Free PMC article.
RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants.
Liang Q, Wang Y, Zhang S, Sun J, Sun W, Li J, Liu Y, Li M, Cheng L, Jiang Y, Wang R, Zhang R, Yang Z, Ren Y, Chen P, Gao P, Yan H, Zhang Z, Zhang Q, Shi X, Wang J, Liu W, Wang X, Ying B, Zhao J, Qi H, Zhang L. Liang Q, et al. Among authors: chen p. iScience. 2022 Apr 15;25(4):104043. doi: 10.1016/j.isci.2022.104043. Epub 2022 Mar 11. iScience. 2022. PMID: 35291264 Free PMC article.
Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2.
Ji Y, Zhang Q, Cheng L, Ge J, Wang R, Fang M, Mucker EM, Chen P, Ma J, Zhang R, Li C, Hammond H, Baracco L, Holbrook M, Frieman M, Zhang Z, Wang X, Hooper JW, Zhang L, Zhu Q. Ji Y, et al. Among authors: chen p. Front Immunol. 2022 Sep 14;13:980435. doi: 10.3389/fimmu.2022.980435. eCollection 2022. Front Immunol. 2022. PMID: 36189212 Free PMC article.
Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants.
Ju B, Zhang Q, Wang Z, Aw ZQ, Chen P, Zhou B, Wang R, Ge X, Lv Q, Cheng L, Zhang R, Wong YH, Chen H, Wang H, Shan S, Liao X, Shi X, Liu L, Chu JJH, Wang X, Zhang Z, Zhang L. Ju B, et al. Among authors: chen p, chen h. Nat Immunol. 2023 Apr;24(4):690-699. doi: 10.1038/s41590-023-01449-6. Epub 2023 Mar 13. Nat Immunol. 2023. PMID: 36914890 Free PMC article.
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