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Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses.
Banach BB, Cerutti G, Fahad AS, Shen CH, de Souza MO, Katsamba PS, Tsybovsky Y, Wang P, Nair MS, Huang Y, Urdániz IMF, Steiner PJ, Gutiérrez-González M, Liu L, López Acevedo SN, Nazzari A, Wolfe JR, Luo Y, Olia AS, Teng IT, Yu J, Zhou T, Reddem ER, Bimela J, Pan X, Madan B, Laflin AD, Nimrania R, Yuen KT, Whitehead TA, Ho DD, Kwong PD, Shapiro L, DeKosky BJ. Banach BB, et al. Among authors: dekosky bj. bioRxiv [Preprint]. 2021 Jan 3:2020.12.31.424987. doi: 10.1101/2020.12.31.424987. bioRxiv. 2021. PMID: 33442681 Free PMC article. Updated. Preprint.
Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.
Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Lopez Acevedo SN, Madan B, de Souza MO, Pan X, Wang P, Wolfe JR, Yin M, Ho DD, Phung E, DiPiazza A, Chang L, Abiona O, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L, Kwong PD. Zhou T, et al. Among authors: dekosky bj. bioRxiv [Preprint]. 2020 Jun 23:2020.06.22.166033. doi: 10.1101/2020.06.22.166033. bioRxiv. 2020. PMID: 32596696 Free PMC article. Updated. Preprint.
Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.
Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Acevedo SNL, Madan B, de Souza MO, Pan X, Wang P, Wolfe JR, Yin M, Ho DD, Phung E, DiPiazza A, Chang L, Abiona O, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L, Kwong PD. Zhou T, et al. Among authors: dekosky bj. SSRN [Preprint]. 2020 Jul 21:3639618. doi: 10.2139/ssrn.3639618. SSRN. 2020. PMID: 32742241 Free PMC article. Updated. Preprint.
Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.
Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Lopez Acevedo SN, Madan B, Oliveira de Souza M, Pan X, Wang P, Wolfe JR, Yin M, Ho DD, Phung E, DiPiazza A, Chang LA, Abiona OM, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L, Kwong PD. Zhou T, et al. Among authors: dekosky bj. Cell Rep. 2020 Oct 27;33(4):108322. doi: 10.1016/j.celrep.2020.108322. Epub 2020 Oct 12. Cell Rep. 2020. PMID: 33091382 Free PMC article.
Antibody-guided structure-based vaccines.
Kwong PD, DeKosky BJ, Ulmer JB. Kwong PD, et al. Among authors: dekosky bj. Semin Immunol. 2020 Aug;50:101428. doi: 10.1016/j.smim.2020.101428. Epub 2020 Nov 24. Semin Immunol. 2020. PMID: 33246736 Review.
Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.
Madan B, Zhang B, Xu K, Chao CW, O'Dell S, Wolfe JR, Chuang GY, Fahad AS, Geng H, Kong R, Louder MK, Nguyen TD, Rawi R, Schön A, Sheng Z, Nimrania R, Wang Y, Zhou T, Lin BC, Doria-Rose NA, Shapiro L, Kwong PD, DeKosky BJ. Madan B, et al. Among authors: dekosky bj. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2011653118. doi: 10.1073/pnas.2011653118. Proc Natl Acad Sci U S A. 2021. PMID: 33649208 Free PMC article.
Functional Profiling of Antibody Immune Repertoires in Convalescent Zika Virus Disease Patients.
Fahad AS, Timm MR, Madan B, Burgomaster KE, Dowd KA, Normandin E, Gutiérrez-González MF, Pennington JM, De Souza MO, Henry AR, Laboune F, Wang L, Ambrozak DR, Gordon IJ, Douek DC, Ledgerwood JE, Graham BS, Castilho LR, Pierson TC, Mascola JR, DeKosky BJ. Fahad AS, et al. Among authors: dekosky bj. Front Immunol. 2021 Feb 24;12:615102. doi: 10.3389/fimmu.2021.615102. eCollection 2021. Front Immunol. 2021. PMID: 33732238 Free PMC article.
Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.
Chuang GY, Shen CH, Cheung CS, Gorman J, Creanga A, Joyce MG, Leung K, Rawi R, Wang L, Yang ES, Yang Y, Zhang B, Zhang Y, Kanekiyo M, Zhou T, DeKosky BJ, Graham BS, Mascola JR, Kwong PD. Chuang GY, et al. Among authors: dekosky bj. Front Immunol. 2021 May 31;12:662909. doi: 10.3389/fimmu.2021.662909. eCollection 2021. Front Immunol. 2021. PMID: 34135892 Free PMC article.
51 results