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Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses.
Banach BB, Cerutti G, Fahad AS, Shen CH, de Souza MO, Katsamba PS, Tsybovsky Y, Wang P, Nair MS, Huang Y, Urdániz IMF, Steiner PJ, Gutiérrez-González M, Liu L, López Acevedo SN, Nazzari A, Wolfe JR, Luo Y, Olia AS, Teng IT, Yu J, Zhou T, Reddem ER, Bimela J, Pan X, Madan B, Laflin AD, Nimrania R, Yuen KT, Whitehead TA, Ho DD, Kwong PD, Shapiro L, DeKosky BJ. Banach BB, et al. Among authors: huang y. bioRxiv [Preprint]. 2021 Jan 3:2020.12.31.424987. doi: 10.1101/2020.12.31.424987. bioRxiv. 2021. PMID: 33442681 Free PMC article. Updated. Preprint.
The HIV-1 vaccine race.
Ho DD, Huang Y. Ho DD, et al. Among authors: huang y. Cell. 2002 Jul 26;110(2):135-8. doi: 10.1016/s0092-8674(02)00832-2. Cell. 2002. PMID: 12150921 Free article. Review.
Engineering multi-specific antibodies against HIV-1.
Padte NN, Yu J, Huang Y, Ho DD. Padte NN, et al. Among authors: huang y. Retrovirology. 2018 Aug 29;15(1):60. doi: 10.1186/s12977-018-0439-9. Retrovirology. 2018. PMID: 30157871 Free PMC article. Review.
Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids.
Han Y, Yang L, Duan X, Duan F, Nilsson-Payant BE, Yaron TM, Wang P, Tang X, Zhang T, Zhao Z, Bram Y, Redmond D, Houghton S, Nguyen D, Xu D, Wang X, Uhl S, Huang Y, Johnson JL, Xiang J, Wang H, Pan FC, Cantley LC, tenOever BR, Ho DD, Evans T, Schwartz RE, Chen HJ, Chen S. Han Y, et al. Among authors: huang y. bioRxiv [Preprint]. 2020 May 5:2020.05.05.079095. doi: 10.1101/2020.05.05.079095. bioRxiv. 2020. PMID: 32511403 Free PMC article. Preprint.
Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike.
Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Liu L, et al. Among authors: huang y. bioRxiv [Preprint]. 2020 Jul 16:2020.06.17.153486. doi: 10.1101/2020.06.17.153486. bioRxiv. 2020. PMID: 32587975 Free PMC article. Updated. Preprint.
Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike.
Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Liu L, et al. Among authors: huang y. Nature. 2020 Aug;584(7821):450-456. doi: 10.1038/s41586-020-2571-7. Epub 2020 Jul 22. Nature. 2020. PMID: 32698192
Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors.
Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Iketani S, et al. Among authors: huang y. bioRxiv [Preprint]. 2020 Aug 4:2020.08.03.235291. doi: 10.1101/2020.08.03.235291. bioRxiv. 2020. PMID: 32793898 Free PMC article. Updated. Preprint.
A simplified cell-based assay to identify coronavirus 3CL protease inhibitors.
Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Nair MS, Huang Y, Tay NES, Rovis T, Yang HW, Stockwell BR, Ho DD, Chavez A. Resnick SJ, et al. Among authors: huang y. bioRxiv [Preprint]. 2020 Aug 29:2020.08.29.272864. doi: 10.1101/2020.08.29.272864. bioRxiv. 2020. PMID: 32869020 Free PMC article. Preprint.
SARS-CoV-2 neutralizing antibody responses are more robust in patients with severe disease.
Wang P, Liu L, Nair MS, Yin MT, Luo Y, Wang Q, Yuan T, Mori K, Solis AG, Yamashita M, Garg A, Purpura LJ, Laracy JC, Yu J, Joshua-Tor L, Sodroski J, Huang Y, Ho DD. Wang P, et al. Among authors: huang y. Emerg Microbes Infect. 2020 Dec;9(1):2091-2093. doi: 10.1080/22221751.2020.1823890. Emerg Microbes Infect. 2020. PMID: 32930052 Free PMC article.
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