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Metabolic adaptation in hypoxia and cancer.
Paredes F, Williams HC, San Martin A. Paredes F, et al. Cancer Lett. 2021 Apr 1;502:133-142. doi: 10.1016/j.canlet.2020.12.020. Epub 2021 Jan 11. Cancer Lett. 2021. PMID: 33444690 Free PMC article. Review.
HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor.
Paredes F, Parra V, Torrealba N, Navarro-Marquez M, Gatica D, Bravo-Sagua R, Troncoso R, Pennanen C, Quiroga C, Chiong M, Caesar C, Taylor WR, Molgó J, San Martin A, Jaimovich E, Lavandero S. Paredes F, et al. Free Radic Biol Med. 2016 Jan;90:206-18. doi: 10.1016/j.freeradbiomed.2015.11.024. Epub 2015 Nov 23. Free Radic Biol Med. 2016. PMID: 26616647 Free PMC article.
Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer.
Paredes F, Sheldon K, Lassègue B, Williams HC, Faidley EA, Benavides GA, Torres G, Sanhueza-Olivares F, Yeligar SM, Griendling KK, Darley-Usmar V, San Martin A. Paredes F, et al. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1789-1794. doi: 10.1073/pnas.1720693115. Epub 2018 Feb 6. Proc Natl Acad Sci U S A. 2018. PMID: 29434038 Free PMC article.
Reply to Bailey et al.: New perspectives on the novel role of the Poldip2/ACSM1 axis in a functional mammalian lipoylation salvage pathway.
Paredes F, Lassègue B, Williams HC, Faidley EA, Benavides GA, Yeligar SM, Griendling KK, Darley-Usmar V, San Martin A. Paredes F, et al. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):E7460-E7461. doi: 10.1073/pnas.1807968115. Epub 2018 Jul 24. Proc Natl Acad Sci U S A. 2018. PMID: 30042216 Free PMC article. No abstract available.
Poldip2 takes a central role in metabolic reprograming.
Paredes F, Suster I, Martin AS. Paredes F, et al. Oncoscience. 2018 Jun 23;5(5-6):130-131. doi: 10.18632/oncoscience.419. eCollection 2018 May. Oncoscience. 2018. PMID: 30035163 Free PMC article. No abstract available.
Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics.
Bravo R, Gutierrez T, Paredes F, Gatica D, Rodriguez AE, Pedrozo Z, Chiong M, Parra V, Quest AF, Rothermel BA, Lavandero S. Bravo R, et al. Among authors: paredes f. Int J Biochem Cell Biol. 2012 Jan;44(1):16-20. doi: 10.1016/j.biocel.2011.10.012. Epub 2011 Nov 2. Int J Biochem Cell Biol. 2012. PMID: 22064245 Free PMC article. Review.
96 results