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MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage.
Kalev P, Hyer ML, Gross S, Konteatis Z, Chen CC, Fletcher M, Lein M, Aguado-Fraile E, Frank V, Barnett A, Mandley E, Goldford J, Chen Y, Sellers K, Hayes S, Lizotte K, Quang P, Tuncay Y, Clasquin M, Peters R, Weier J, Simone E, Murtie J, Liu W, Nagaraja R, Dang L, Sui Z, Biller SA, Travins J, Marks KM, Marjon K. Kalev P, et al. Among authors: lein m. Cancer Cell. 2021 Feb 8;39(2):209-224.e11. doi: 10.1016/j.ccell.2020.12.010. Epub 2021 Jan 14. Cancer Cell. 2021. PMID: 33450196 Free article.
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads.
Li M, Konteatis Z, Nagaraja N, Chen Y, Zhou S, Ma G, Gross S, Marjon K, Hyer ML, Mandley E, Lein M, Padyana AK, Jin L, Tong S, Peters R, Murtie J, Travins J, Medeiros M, Liu P, Frank V, Judd ET, Biller SA, Marks KM, Sui Z, Reznik SK. Li M, et al. Among authors: lein m. J Med Chem. 2022 Mar 24;65(6):4600-4615. doi: 10.1021/acs.jmedchem.1c01595. Epub 2022 Mar 16. J Med Chem. 2022. PMID: 35293760
Impacts of a health literacy-informed intervention in people with chronic obstructive pulmonary disease (COPD) on hospitalization, health literacy, self-management, quality of life, and health costs - A randomized controlled trial.
Borge CR, Larsen MH, Osborne RH, Aas E, Kolle IT, Reinertsen R, Lein MP, Thörn M, Lind RM, Groth M, Strand O, Andersen MH, Moum T, Engebretsen E, Wahl AK. Borge CR, et al. Among authors: lein mp. Patient Educ Couns. 2024 Jun;123:108220. doi: 10.1016/j.pec.2024.108220. Epub 2024 Feb 16. Patient Educ Couns. 2024. PMID: 38458089 Clinical Trial.
How tech-savvy employees make the difference in core facilities: Recognizing core facility expertise with dedicated career tracks: Recognizing core facility expertise with dedicated career tracks.
Lippens S, Audenaert D, Botzki A, Derveaux S, Ghesquière B, Goeminne G, Hassanzadeh R, Haustraete J, Impens F, Lamote J, Munck S, Vandamme N, Van Isterdael G, Lein M, Van Minnebruggen G. Lippens S, et al. Among authors: lein m. EMBO Rep. 2022 Jun 7;23(6):e55094. doi: 10.15252/embr.202255094. Epub 2022 Jun 1. EMBO Rep. 2022. PMID: 35652151 Free PMC article.
Magnetic-Field Effect in High-Order Above-Threshold Ionization.
Lin K, Brennecke S, Ni H, Chen X, Hartung A, Trabert D, Fehre K, Rist J, Tong XM, Burgdörfer J, Schmidt LPH, Schöffler MS, Jahnke T, Kunitski M, He F, Lein M, Eckart S, Dörner R. Lin K, et al. Among authors: lein m. Phys Rev Lett. 2022 Jan 14;128(2):023201. doi: 10.1103/PhysRevLett.128.023201. Phys Rev Lett. 2022. PMID: 35089761
Nonadiabatic Strong Field Ionization of Atomic Hydrogen.
Trabert D, Anders N, Brennecke S, Schöffler MS, Jahnke T, Schmidt LPH, Kunitski M, Lein M, Dörner R, Eckart S. Trabert D, et al. Among authors: lein m. Phys Rev Lett. 2021 Dec 31;127(27):273201. doi: 10.1103/PhysRevLett.127.273201. Phys Rev Lett. 2021. PMID: 35061406
278 results