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Rapid Development of SARS-CoV-2 Spike Protein Receptor-Binding Domain Self-Assembled Nanoparticle Vaccine Candidates.
Kang YF, Sun C, Zhuang Z, Yuan RY, Zheng Q, Li JP, Zhou PP, Chen XC, Liu Z, Zhang X, Yu XH, Kong XW, Zhu QY, Zhong Q, Xu M, Zhong NS, Zeng YX, Feng GK, Ke C, Zhao JC, Zeng MS. Kang YF, et al. Among authors: zheng q. ACS Nano. 2021 Feb 23;15(2):2738-2752. doi: 10.1021/acsnano.0c08379. Epub 2021 Jan 19. ACS Nano. 2021. PMID: 33464829 Free article.
A shared N-terminal hydrophobic tail for the formation of nanoparticulates.
Zhang X, Wang K, Lin Q, Zheng M, Li Q, Li T, Hong Q, Zheng Q, Yu H, Gu Y, Li S, Xia N. Zhang X, et al. Among authors: zheng q, zheng m. Nanomedicine (Lond). 2016 Sep;11(17):2289-303. doi: 10.2217/nnm-2016-0146. Epub 2016 Aug 8. Nanomedicine (Lond). 2016. PMID: 27499052
SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates.
Li T, Zheng Q, Yu H, Wu D, Xue W, Xiong H, Huang X, Nie M, Yue M, Rong R, Zhang S, Zhang Y, Wu Y, Wang S, Zha Z, Chen T, Deng T, Wang Y, Zhang T, Chen Y, Yuan Q, Zhao Q, Zhang J, Gu Y, Li S, Xia N. Li T, et al. Among authors: zheng q. Emerg Microbes Infect. 2020 Dec;9(1):2076-2090. doi: 10.1080/22221751.2020.1821583. Emerg Microbes Infect. 2020. PMID: 32897177 Free PMC article.
A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters.
Wu Y, Huang X, Yuan L, Wang S, Zhang Y, Xiong H, Chen R, Ma J, Qi R, Nie M, Xu J, Zhang Z, Chen L, Wei M, Zhou M, Cai M, Shi Y, Zhang L, Yu H, Hong J, Wang Z, Hong Y, Yue M, Li Z, Chen D, Zheng Q, Li S, Chen Y, Cheng T, Zhang J, Zhang T, Zhu H, Zhao Q, Yuan Q, Guan Y, Xia N. Wu Y, et al. Among authors: zheng q. Sci Transl Med. 2021 Aug 11;13(606):eabg1143. doi: 10.1126/scitranslmed.abg1143. Epub 2021 Jul 20. Sci Transl Med. 2021. PMID: 34285130 Free PMC article.
Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Li T, Xue W, Zheng Q, Song S, Yang C, Xiong H, Zhang S, Hong M, Zhang Y, Yu H, Zhang Y, Sun H, Huang Y, Deng T, Chi X, Li J, Wang S, Zhou L, Chen T, Wang Y, Cheng T, Zhang T, Yuan Q, Zhao Q, Zhang J, McLellan JS, Zhou ZH, Zhang Z, Li S, Gu Y, Xia N. Li T, et al. Among authors: zheng q. Nat Commun. 2021 Sep 27;12(1):5652. doi: 10.1038/s41467-021-25997-3. Nat Commun. 2021. PMID: 34580306 Free PMC article.
A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice.
Liu L, Chen T, Zhou L, Sun J, Li Y, Nie M, Xiong H, Zhu Y, Xue W, Wu Y, Li T, Zhang T, Kong Z, Yu H, Zhang J, Gu Y, Zheng Q, Zhao Q, Xia N, Li S. Liu L, et al. Among authors: zheng q. Front Microbiol. 2022 Apr 26;13:854630. doi: 10.3389/fmicb.2022.854630. eCollection 2022. Front Microbiol. 2022. PMID: 35558112 Free PMC article.
Protective anti-gB neutralizing antibodies targeting two vulnerable sites for EBV-cell membrane fusion.
Zhang X, Hong J, Zhong L, Wu Q, Zhang S, Zhu Q, Chen H, Wei D, Li R, Zhang W, Zhang X, Wang G, Zhou X, Chen J, Kang Y, Zha Z, Duan X, Huang Y, Sun C, Kong X, Zhou Y, Chen Y, Ye X, Feng Q, Li S, Xiang T, Gao S, Zeng MS, Zheng Q, Chen Y, Zeng YX, Xia N, Xu M. Zhang X, et al. Among authors: zheng q. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2202371119. doi: 10.1073/pnas.2202371119. Epub 2022 Aug 2. Proc Natl Acad Sci U S A. 2022. PMID: 35917353 Free PMC article.
The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N. Xiong H, et al. Among authors: zheng q, zheng z. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2204256119. doi: 10.1073/pnas.2204256119. Epub 2022 Aug 16. Proc Natl Acad Sci U S A. 2022. PMID: 35972965 Free PMC article.
7,939 results