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Antibody-mediated depletion of viral reservoirs is limited in SIV-infected macaques treated early with antiretroviral therapy.
Swanstrom AE, Immonen TT, Oswald K, Pyle C, Thomas JA, Bosche WJ, Silipino L, Hull M, Newman L, Coalter V, Wiles A, Wiles R, Kiser J, Morcock DR, Shoemaker R, Fast R, Breed MW, Kramer J, Donohue D, Malys T, Fennessey CM, Trubey CM, Deleage C, Estes JD, Lifson JD, Keele BF, Del Prete GQ. Swanstrom AE, et al. Among authors: bosche wj. J Clin Invest. 2021 Mar 15;131(6):e142421. doi: 10.1172/JCI142421. J Clin Invest. 2021. PMID: 33465055 Free PMC article.
Strict conservation of the retroviral nucleocapsid protein zinc finger is strongly influenced by its role in viral infection processes: characterization of HIV-1 particles containing mutant nucleocapsid zinc-coordinating sequences.
Gorelick RJ, Gagliardi TD, Bosche WJ, Wiltrout TA, Coren LV, Chabot DJ, Lifson JD, Henderson LE, Arthur LO. Gorelick RJ, et al. Among authors: bosche wj. Virology. 1999 Mar 30;256(1):92-104. doi: 10.1006/viro.1999.9629. Virology. 1999. PMID: 10087230 Free article.
Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys.
Barouch DH, Ghneim K, Bosche WJ, Li Y, Berkemeier B, Hull M, Bhattacharyya S, Cameron M, Liu J, Smith K, Borducchi E, Cabral C, Peter L, Brinkman A, Shetty M, Li H, Gittens C, Baker C, Wagner W, Lewis MG, Colantonio A, Kang HJ, Li W, Lifson JD, Piatak M Jr, Sekaly RP. Barouch DH, et al. Among authors: bosche wj. Cell. 2016 Apr 21;165(3):656-67. doi: 10.1016/j.cell.2016.03.021. Epub 2016 Apr 13. Cell. 2016. PMID: 27085913 Free PMC article.
Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus.
Liu J, Ghneim K, Sok D, Bosche WJ, Li Y, Chipriano E, Berkemeier B, Oswald K, Borducchi E, Cabral C, Peter L, Brinkman A, Shetty M, Jimenez J, Mondesir J, Lee B, Giglio P, Chandrashekar A, Abbink P, Colantonio A, Gittens C, Baker C, Wagner W, Lewis MG, Li W, Sekaly RP, Lifson JD, Burton DR, Barouch DH. Liu J, et al. Among authors: bosche wj. Science. 2016 Sep 2;353(6303):1045-1049. doi: 10.1126/science.aag0491. Epub 2016 Aug 18. Science. 2016. PMID: 27540005 Free PMC article.
Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy.
Fennessey CM, Pinkevych M, Immonen TT, Reynaldi A, Venturi V, Nadella P, Reid C, Newman L, Lipkey L, Oswald K, Bosche WJ, Trivett MT, Ohlen C, Ott DE, Estes JD, Del Prete GQ, Lifson JD, Davenport MP, Keele BF. Fennessey CM, et al. Among authors: bosche wj. PLoS Pathog. 2017 May 4;13(5):e1006359. doi: 10.1371/journal.ppat.1006359. eCollection 2017 May. PLoS Pathog. 2017. PMID: 28472156 Free PMC article.
Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.
Fisher BS, Green RR, Brown RR, Wood MP, Hensley-McBain T, Fisher C, Chang J, Miller AD, Bosche WJ, Lifson JD, Mavigner M, Miller CJ, Gale M Jr, Silvestri G, Chahroudi A, Klatt NR, Sodora DL. Fisher BS, et al. Among authors: bosche wj. PLoS Pathog. 2018 Feb 21;14(2):e1006871. doi: 10.1371/journal.ppat.1006871. eCollection 2018 Feb. PLoS Pathog. 2018. PMID: 29466439 Free PMC article.
27 results