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The antimicrobial potential of cannabidiol.
Blaskovich MAT, Kavanagh AM, Elliott AG, Zhang B, Ramu S, Amado M, Lowe GJ, Hinton AO, Pham DMT, Zuegg J, Beare N, Quach D, Sharp MD, Pogliano J, Rogers AP, Lyras D, Tan L, West NP, Crawford DW, Peterson ML, Callahan M, Thurn M. Blaskovich MAT, et al. Among authors: lyras d. Commun Biol. 2021 Jan 19;4(1):7. doi: 10.1038/s42003-020-01530-y. Commun Biol. 2021. PMID: 33469147 Free PMC article.
Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles targeting Clostridioides (Clostridium) difficile: Synthesis, antibacterial evaluation and an in vivo C. difficile infection model.
Tague AJ, Putsathit P, Hutton ML, Hammer KA, Wales SM, Knight DR, Riley TV, Lyras D, Keller PA, Pyne SG. Tague AJ, et al. Among authors: lyras d. Eur J Med Chem. 2019 May 15;170:203-224. doi: 10.1016/j.ejmech.2019.02.068. Epub 2019 Mar 1. Eur J Med Chem. 2019. PMID: 30901686
Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease.
Mileto SJ, Jardé T, Childress KO, Jensen JL, Rogers AP, Kerr G, Hutton ML, Sheedlo MJ, Bloch SC, Shupe JA, Horvay K, Flores T, Engel R, Wilkins S, McMurrick PJ, Lacy DB, Abud HE, Lyras D. Mileto SJ, et al. Among authors: lyras d. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8064-8073. doi: 10.1073/pnas.1915255117. Epub 2020 Mar 20. Proc Natl Acad Sci U S A. 2020. PMID: 32198200 Free PMC article.
A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.
Blaskovich MAT, Hansford KA, Butler MS, Ramu S, Kavanagh AM, Jarrad AM, Prasetyoputri A, Pitt ME, Huang JX, Lindahl F, Ziora ZM, Bradford T, Muldoon C, Rajaratnam P, Pelingon R, Edwards DJ, Zhang B, Amado M, Elliott AG, Zuegg J, Coin L, Woischnig AK, Khanna N, Breidenstein E, Stincone A, Mason C, Khan N, Cho HK, Karau MJ, Greenwood-Quaintance KE, Patel R, Wootton M, James ML, Hutton ML, Lyras D, Ogunniyi AD, Mahdi LK, Trott DJ, Wu X, Niles S, Lewis K, Smith JR, Barber KE, Yim J, Rice SA, Rybak MJ, Ishmael CR, Hori KR, Bernthal NM, Francis KP, Roberts JA, Paterson DL, Cooper MA. Blaskovich MAT, et al. Among authors: lyras d. Sci Transl Med. 2022 Sep 14;14(662):eabj2381. doi: 10.1126/scitranslmed.abj2381. Epub 2022 Sep 14. Sci Transl Med. 2022. PMID: 36103517
Multi-omics analysis of hospital-acquired diarrhoeal patients reveals biomarkers of enterococcal proliferation and Clostridioides difficile infection.
Bosnjak M, Karpe AV, Van TTH, Kotsanas D, Jenkin GA, Costello SP, Johanesen P, Moore RJ, Beale DJ, Srikhanta YN, Palombo EA, Larcombe S, Lyras D. Bosnjak M, et al. Among authors: lyras d. Nat Commun. 2023 Nov 25;14(1):7737. doi: 10.1038/s41467-023-43671-8. Nat Commun. 2023. PMID: 38007555 Free PMC article.
Methods for gene cloning and targeted mutagenesis.
Carter GP, Lyras D, Poon R, Howarth PM, Rood JI. Carter GP, et al. Among authors: lyras d. Methods Mol Biol. 2010;646:183-201. doi: 10.1007/978-1-60327-365-7_12. Methods Mol Biol. 2010. PMID: 20597010
175 results