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Pentraxin-3 is upregulated in the central nervous system during MS and EAE, but does not modulate experimental neurological disease.
Ummenthum K, Peferoen LA, Finardi A, Baker D, Pryce G, Mantovani A, Bsibsi M, Bottazzi B, Peferoen-Baert R, van der Valk P, Garlanda C, Kipp M, Furlan R, van Noort JM, Amor S. Ummenthum K, et al. Eur J Immunol. 2016 Mar;46(3):701-11. doi: 10.1002/eji.201545950. Epub 2015 Dec 14. Eur J Immunol. 2016. PMID: 26576501 Free article.
Lesional-targeting of neuroprotection to the inflammatory penumbra in experimental multiple sclerosis.
Al-Izki S, Pryce G, Hankey DJ, Lidster K, von Kutzleben SM, Browne L, Clutterbuck L, Posada C, Edith Chan AW, Amor S, Perkins V, Gerritsen WH, Ummenthum K, Peferoen-Baert R, van der Valk P, Montoya A, Joel SP, Garthwaite J, Giovannoni G, Selwood DL, Baker D. Al-Izki S, et al. Brain. 2014 Jan;137(Pt 1):92-108. doi: 10.1093/brain/awt324. Epub 2013 Nov 27. Brain. 2014. PMID: 24287115
Epstein Barr virus is not a characteristic feature in the central nervous system in established multiple sclerosis.
Peferoen LA, Lamers F, Lodder LN, Gerritsen WH, Huitinga I, Melief J, Giovannoni G, Meier U, Hintzen RQ, Verjans GM, van Nierop GP, Vos W, Peferoen-Baert RM, Middeldorp JM, van der Valk P, Amor S. Peferoen LA, et al. Among authors: peferoen baert rm. Brain. 2010 May;133(Pt 5):e137. doi: 10.1093/brain/awp296. Epub 2009 Nov 16. Brain. 2010. PMID: 19917644 No abstract available.