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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Cell. 2021 Feb 4;184(3):655-674.e27. doi: 10.1016/j.cell.2020.12.024. Epub 2021 Jan 25.
Cell. 2021.
PMID: 33497611
Free PMC article.
Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities.
De Meulemeester AS, Heylen L, Siekierska A, Mills JD, Romagnolo A, Van Der Wel NN, Aronica E, de Witte PAM.
De Meulemeester AS, et al.
Front Cell Dev Biol. 2022 Sep 27;10:952832. doi: 10.3389/fcell.2022.952832. eCollection 2022.
Front Cell Dev Biol. 2022.
PMID: 36238691
Free PMC article.
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Modeling Neurodevelopmental Disorders and Epilepsy Caused by Loss of Function of kif2a in Zebrafish.
Partoens M, De Meulemeester AS, Giong HK, Pham DH, Lee JS, de Witte PA, Siekierska A.
Partoens M, et al. Among authors: de meulemeester as.
eNeuro. 2021 Sep 7;8(5):ENEURO.0055-21.2021. doi: 10.1523/ENEURO.0055-21.2021. Print 2021 Sep-Oct.
eNeuro. 2021.
PMID: 34404749
Free PMC article.
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Pericardial Injection of Kainic Acid Induces a Chronic Epileptic State in Larval Zebrafish.
Heylen L, Pham DH, De Meulemeester AS, Samarut É, Skiba A, Copmans D, Kazwiny Y, Vanden Berghe P, de Witte PAM, Siekierska A.
Heylen L, et al. Among authors: de meulemeester as.
Front Mol Neurosci. 2021 Oct 14;14:753936. doi: 10.3389/fnmol.2021.753936. eCollection 2021.
Front Mol Neurosci. 2021.
PMID: 34720874
Free PMC article.
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