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Page 1
Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial.
Scriba TJ, Fiore-Gartland A, Penn-Nicholson A, Mulenga H, Kimbung Mbandi S, Borate B, Mendelsohn SC, Hadley K, Hikuam C, Kaskar M, Musvosvi M, Bilek N, Self S, Sumner T, White RG, Erasmus M, Jaxa L, Raphela R, Innes C, Brumskine W, Hiemstra A, Malherbe ST, Hassan-Moosa R, Tameris M, Walzl G, Naidoo K, Churchyard G, Hatherill M; CORTIS-01 Study Team. Scriba TJ, et al. Among authors: hiemstra a. Lancet Infect Dis. 2021 Mar;21(3):354-365. doi: 10.1016/S1473-3099(20)30914-2. Epub 2021 Jan 25. Lancet Infect Dis. 2021. PMID: 33508224 Free PMC article. Clinical Trial.
Prospective evaluation of host biomarkers other than interferon gamma in QuantiFERON Plus supernatants as candidates for the diagnosis of tuberculosis in symptomatic individuals.
Manngo PM, Gutschmidt A, Snyders CI, Mutavhatsindi H, Manyelo CM, Makhoba NS, Ahlers P, Hiemstra A, Stanley K, McAnda S, Kidd M, Malherbe ST, Walzl G, Chegou NN. Manngo PM, et al. Among authors: hiemstra a. J Infect. 2019 Sep;79(3):228-235. doi: 10.1016/j.jinf.2019.07.007. Epub 2019 Jul 15. J Infect. 2019. PMID: 31319143 Free PMC article.
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response.
Penn-Nicholson A, Mbandi SK, Thompson E, Mendelsohn SC, Suliman S, Chegou NN, Malherbe ST, Darboe F, Erasmus M, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Winter J, Murphy M, Wood R, Morrow C, Van Rhijn I, Moody B, Murray M, Andrade BB, Sterling TR, Sutherland J, Naidoo K, Padayatchi N, Walzl G, Hatherill M, Zak D, Scriba TJ; Adolescent Cohort Study team; GC6-74 Consortium; SATVI Clinical and Laboratory Team; ScreenTB Consortium; AE-TBC Consortium; RePORT Brazil Team; Peruvian Household Contacts Cohort Team; CAPRISA IMPRESS team. Penn-Nicholson A, et al. Sci Rep. 2020 May 25;10(1):8629. doi: 10.1038/s41598-020-65043-8. Sci Rep. 2020. PMID: 32451443 Free PMC article.
Higher SARS-CoV-2 seroprevalence in workers with lower socioeconomic status in Cape Town, South Africa.
Shaw JA, Meiring M, Cummins T, Chegou NN, Claassen C, Du Plessis N, Flinn M, Hiemstra A, Kleynhans L, Leukes V, Loxton AG, MacDonald C, Mtala N, Reuter H, Simon D, Stanley K, Tromp G, Preiser W, Malherbe ST, Walzl G. Shaw JA, et al. Among authors: hiemstra a. PLoS One. 2021 Feb 25;16(2):e0247852. doi: 10.1371/journal.pone.0247852. eCollection 2021. PLoS One. 2021. PMID: 33630977 Free PMC article.
Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study.
Mendelsohn SC, Fiore-Gartland A, Penn-Nicholson A, Mulenga H, Mbandi SK, Borate B, Hadley K, Hikuam C, Musvosvi M, Bilek N, Erasmus M, Jaxa L, Raphela R, Nombida O, Kaskar M, Sumner T, White RG, Innes C, Brumskine W, Hiemstra A, Malherbe ST, Hassan-Moosa R, Tameris M, Walzl G, Naidoo K, Churchyard G, Scriba TJ, Hatherill M; CORTIS-HR Study Team. Mendelsohn SC, et al. Among authors: hiemstra a. Lancet Glob Health. 2021 Jun;9(6):e841-e853. doi: 10.1016/S2214-109X(21)00045-0. Epub 2021 Apr 13. Lancet Glob Health. 2021. PMID: 33862012 Free PMC article.
Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis.
Dorman SE, Nahid P, Kurbatova EV, Phillips PPJ, Bryant K, Dooley KE, Engle M, Goldberg SV, Phan HTT, Hakim J, Johnson JL, Lourens M, Martinson NA, Muzanyi G, Narunsky K, Nerette S, Nguyen NV, Pham TH, Pierre S, Purfield AE, Samaneka W, Savic RM, Sanne I, Scott NA, Shenje J, Sizemore E, Vernon A, Waja Z, Weiner M, Swindells S, Chaisson RE; AIDS Clinical Trials Group; Tuberculosis Trials Consortium. Dorman SE, et al. N Engl J Med. 2021 May 6;384(18):1705-1718. doi: 10.1056/NEJMoa2033400. N Engl J Med. 2021. PMID: 33951360 Free PMC article. Clinical Trial.
Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis.
Kotze LA, Beltran CGG, Lang D, Loxton AG, Cooper S, Meiring M, Koegelenberg CFN, Allwood BW, Malherbe ST, Hiemstra AM, Glanzmann B, Kinnear C, Walzl G, du Plessis N. Kotze LA, et al. Among authors: hiemstra am. mSphere. 2021 Aug 25;6(4):e0055221. doi: 10.1128/mSphere.00552-21. Epub 2021 Jul 21. mSphere. 2021. PMID: 34287004 Free PMC article.
Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis.
Mulenga H, Musvosvi M, Mendelsohn SC, Penn-Nicholson A, Kimbung Mbandi S, Fiore-Gartland A, Tameris M, Mabwe S, Africa H, Bilek N, Kafaar F, Khader SA, Carstens B, Hadley K, Hikuam C, Erasmus M, Jaxa L, Raphela R, Nombida O, Kaskar M, Nicol MP, Mbhele S, Van Heerden J, Innes C, Brumskine W, Hiemstra A, Malherbe ST, Hassan-Moosa R, Walzl G, Naidoo K, Churchyard G, Hatherill M, Scriba TJ; CORTIS Study Team. Mulenga H, et al. Among authors: hiemstra a. Am J Respir Crit Care Med. 2021 Dec 15;204(12):1463-1472. doi: 10.1164/rccm.202103-0548OC. Am J Respir Crit Care Med. 2021. PMID: 34520313 Free PMC article.
Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results.
Sutherland JS, van der Spuy G, Gindeh A, Thuong NTT, Namuganga A, Owolabi O, Mayanja-Kizza H, Nsereko M, Thwaites G, Winter J, Dockrell HM, Scriba TJ, Geluk A, Corstjens P, Stanley K, Richardson T, Shaw JA, Smith B, Malherbe ST, Walzl G; TrENDx-TB Consortium. Sutherland JS, et al. Clin Infect Dis. 2022 Jul 6;74(12):2136-2141. doi: 10.1093/cid/ciab839. Clin Infect Dis. 2022. PMID: 34550342 Free PMC article.
Cascade Immune Mechanisms of Protection against Mycobacterium tuberculosis (IMPAc-TB): study protocol for the Household Contact Study in the Western Cape, South Africa.
Hiemstra AM, MacDonald CE, van Rensburg IC, Stanley K, Maasdorp E, Mc Anda S, Tönsing S, Shaw JA, Tromp G, van der Spuy GD, Urdahl KB, Lewinsohn DM, Kuivaniemi H, Du Plessis N, Malherbe ST, Walzl G. Hiemstra AM, et al. BMC Infect Dis. 2022 Apr 15;22(1):381. doi: 10.1186/s12879-022-07349-8. BMC Infect Dis. 2022. PMID: 35428268 Free PMC article.
36 results