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Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction.
Rieunier G, Wu X, Harris LE, Mills JV, Nandakumar A, Colling L, Seraia E, Hatch SB, Ebner DV, Folkes LK, Weyer-Czernilofsky U, Bogenrieder T, Ryan AJ, Macaulay VM. Rieunier G, et al. Among authors: macaulay vm. Cancer Res. 2021 Apr 15;81(8):2128-2141. doi: 10.1158/0008-5472.CAN-20-2860. Epub 2021 Jan 28. Cancer Res. 2021. PMID: 33509941
The type 1 insulin-like growth factor receptor pathway.
Chitnis MM, Yuen JS, Protheroe AS, Pollak M, Macaulay VM. Chitnis MM, et al. Among authors: macaulay vm. Clin Cancer Res. 2008 Oct 15;14(20):6364-70. doi: 10.1158/1078-0432.CCR-07-4879. Clin Cancer Res. 2008. PMID: 18927274 Review.
Can we unlock the potential of IGF-1R inhibition in cancer therapy?
King H, Aleksic T, Haluska P, Macaulay VM. King H, et al. Among authors: macaulay vm. Cancer Treat Rev. 2014 Oct;40(9):1096-105. doi: 10.1016/j.ctrv.2014.07.004. Epub 2014 Aug 4. Cancer Treat Rev. 2014. PMID: 25123819 Free PMC article. Review.
Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling.
Gao S, Bajrami I, Verrill C, Kigozi A, Ouaret D, Aleksic T, Asher R, Han C, Allen P, Bailey D, Feller S, Kashima T, Athanasou N, Blay JY, Schmitz S, Machiels JP, Upile N, Jones TM, Thalmann G, Ashraf SQ, Wilding JL, Bodmer WF, Middleton MR, Ashworth A, Lord CJ, Macaulay VM. Gao S, et al. Among authors: macaulay vm. Cancer Res. 2014 Oct 15;74(20):5866-77. doi: 10.1158/0008-5472.CAN-14-0806. Epub 2014 Aug 28. Cancer Res. 2014. PMID: 25168481 Free article.
83 results