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MAIT cell activation augments adenovirus vector vaccine immunogenicity.
Provine NM, Amini A, Garner LC, Spencer AJ, Dold C, Hutchings C, Silva Reyes L, FitzPatrick MEB, Chinnakannan S, Oguti B, Raymond M, Ulaszewska M, Troise F, Sharpe H, Morgan SB, Hinks TSC, Lambe T, Capone S, Folgori A, Barnes E, Rollier CS, Pollard AJ, Klenerman P. Provine NM, et al. Among authors: troise f. Science. 2021 Jan 29;371(6528):521-526. doi: 10.1126/science.aax8819. Science. 2021. PMID: 33510029 Free PMC article.
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade.
D'Alise AM, Leoni G, Cotugno G, Troise F, Langone F, Fichera I, De Lucia M, Avalle L, Vitale R, Leuzzi A, Bignone V, Di Matteo E, Tucci FG, Poli V, Lahm A, Catanese MT, Folgori A, Colloca S, Nicosia A, Scarselli E. D'Alise AM, et al. Among authors: troise f. Nat Commun. 2019 Jun 19;10(1):2688. doi: 10.1038/s41467-019-10594-2. Nat Commun. 2019. PMID: 31217437 Free PMC article.
A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability.
Leoni G, D'Alise AM, Cotugno G, Langone F, Garzia I, De Lucia M, Fichera I, Vitale R, Bignone V, Tucci FG, Mori F, Leuzzi A, Di Matteo E, Troise F, Abbate A, Merone R, Ruzza V, Diodoro MG, Yadav M, Gordon-Alonso M, Vanhaver C, Panigada M, Soprana E, Siccardi A, Folgori A, Colloca S, van der Bruggen P, Nicosia A, Lahm A, Catanese MT, Scarselli E. Leoni G, et al. Among authors: troise f. Cancer Res. 2020 Sep 15;80(18):3972-3982. doi: 10.1158/0008-5472.CAN-20-1072. Epub 2020 Jul 20. Cancer Res. 2020. PMID: 32690723
Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner.
Provine NM, Amini A, Garner LC, FitzPatrick MEB, Dold C, Silva Reyes L, Chinnakannan S, Oguti B, Raymond M, Troise F, Capone S, Folgori A, Barnes E, Rollier CS, Pollard AJ, Klenerman P. Provine NM, et al. Among authors: troise f. Eur J Immunol. 2022 May;52(5):835-837. doi: 10.1002/eji.202149367. Epub 2022 Jan 17. Eur J Immunol. 2022. PMID: 34958459 Free article.
Adenovirus Encoded Adjuvant (AdEnA) anti-CTLA-4, a novel strategy to improve Adenovirus based vaccines against infectious diseases and cancer.
D'Alise AM, Nocchi L, Garzia I, Seclì L, Infante L, Troise F, Cotugno G, Allocca S, Romano G, Lahm A, Leoni G, Sasso E, Scarselli E, Nicosia A. D'Alise AM, et al. Among authors: troise f. Front Immunol. 2023 Apr 26;14:1156714. doi: 10.3389/fimmu.2023.1156714. eCollection 2023. Front Immunol. 2023. PMID: 37180141 Free PMC article.
Maximizing cancer therapy via complementary mechanisms of immune activation: PD-1 blockade, neoantigen vaccination, and Tregs depletion.
D'Alise AM, Leoni G, De Lucia M, Langone F, Nocchi L, Tucci FG, Micarelli E, Cotugno G, Troise F, Garzia I, Vitale R, Bignone V, Di Matteo E, Bartolomeo R, Charych DH, Lahm A, Zalevsky J, Nicosia A, Scarselli E. D'Alise AM, et al. Among authors: troise f. J Immunother Cancer. 2021 Nov;9(11):e003480. doi: 10.1136/jitc-2021-003480. J Immunother Cancer. 2021. PMID: 34824160 Free PMC article.
Tumor Burden Dictates the Neoantigen Features Required to Generate an Effective Cancer Vaccine.
Garzia I, Nocchi L, Avalle L, Troise F, Leoni G, Seclì L, Antonucci L, Cotugno G, Allocca S, Romano G, Conti L, Caiazza C, Mallardo M, Poli V, Scarselli E, D'Alise AM. Garzia I, et al. Among authors: troise f. Cancer Immunol Res. 2024 Apr 2;12(4):440-452. doi: 10.1158/2326-6066.CIR-23-0609. Cancer Immunol Res. 2024. PMID: 38331413 Free PMC article.
Vector Aided Microenvironment programming (VAMP): reprogramming the TME with MVA virus expressing IL-12 for effective antitumor activity.
Seclì L, Infante L, Nocchi L, De Lucia M, Cotugno G, Leoni G, Micarelli E, Garzia I, Avalle L, Sdruscia G, Troise F, Allocca S, Romano G, Scarselli E, D'Alise AM. Seclì L, et al. Among authors: troise f. J Immunother Cancer. 2023 Apr;11(4):e006718. doi: 10.1136/jitc-2023-006718. J Immunother Cancer. 2023. PMID: 37117006 Free PMC article.
Development of a Potency Assay for Nous-209, a Multivalent Neoantigens-Based Genetic Cancer Vaccine.
Bartolomeo R, Troise F, Allocca S, Sdruscia G, Vitale R, Bignone V, Petrone AM, Romano G, D'Alise AM, Ruzza V, Garzia I, Leoni G, Merone R, Lanzaro F, Colloca S, Siani L, Scarselli E, Cotugno G. Bartolomeo R, et al. Among authors: troise f. Vaccines (Basel). 2024 Mar 19;12(3):325. doi: 10.3390/vaccines12030325. Vaccines (Basel). 2024. PMID: 38543959 Free PMC article.
25 results