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Vaccine Therapies for Cancer: Then and Now.
Morse MA, Gwin WR 3rd, Mitchell DA. Morse MA, et al. Among authors: mitchell da. Target Oncol. 2021 Mar;16(2):121-152. doi: 10.1007/s11523-020-00788-w. Epub 2021 Jan 29. Target Oncol. 2021. PMID: 33512679 Free PMC article. Review.
An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme.
Sampson JH, Archer GE, Mitchell DA, Heimberger AB, Herndon JE 2nd, Lally-Goss D, McGehee-Norman S, Paolino A, Reardon DA, Friedman AH, Friedman HS, Bigner DD. Sampson JH, et al. Among authors: mitchell da. Mol Cancer Ther. 2009 Oct;8(10):2773-9. doi: 10.1158/1535-7163.MCT-09-0124. Mol Cancer Ther. 2009. PMID: 19825799 Free PMC article. Clinical Trial.
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma.
Sampson JH, Heimberger AB, Archer GE, Aldape KD, Friedman AH, Friedman HS, Gilbert MR, Herndon JE 2nd, McLendon RE, Mitchell DA, Reardon DA, Sawaya R, Schmittling RJ, Shi W, Vredenburgh JJ, Bigner DD. Sampson JH, et al. Among authors: mitchell da. J Clin Oncol. 2010 Nov 1;28(31):4722-9. doi: 10.1200/JCO.2010.28.6963. Epub 2010 Oct 4. J Clin Oncol. 2010. PMID: 20921459 Free PMC article. Clinical Trial.
Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma.
Sampson JH, Aldape KD, Archer GE, Coan A, Desjardins A, Friedman AH, Friedman HS, Gilbert MR, Herndon JE, McLendon RE, Mitchell DA, Reardon DA, Sawaya R, Schmittling R, Shi W, Vredenburgh JJ, Bigner DD, Heimberger AB. Sampson JH, et al. Among authors: mitchell da. Neuro Oncol. 2011 Mar;13(3):324-33. doi: 10.1093/neuonc/noq157. Epub 2010 Dec 10. Neuro Oncol. 2011. PMID: 21149254 Free PMC article. Clinical Trial.
Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice.
Sanchez-Perez LA, Choi BD, Archer GE, Cui X, Flores C, Johnson LA, Schmittling RJ, Snyder D, Herndon JE 2nd, Bigner DD, Mitchell DA, Sampson JH. Sanchez-Perez LA, et al. Among authors: mitchell da. PLoS One. 2013;8(3):e59082. doi: 10.1371/journal.pone.0059082. Epub 2013 Mar 18. PLoS One. 2013. PMID: 23527092 Free PMC article.
BLyS levels correlate with vaccine-induced antibody titers in patients with glioblastoma lymphodepleted by therapeutic temozolomide.
Sanchez-Perez L, Choi BD, Reap EA, Sayour EJ, Norberg P, Schmittling RJ, Archer GE, Herndon JE 2nd, Mitchell DA, Heimberger AB, Bigner DD, Sampson JH. Sanchez-Perez L, et al. Among authors: mitchell da. Cancer Immunol Immunother. 2013 Jun;62(6):983-7. doi: 10.1007/s00262-013-1405-y. Epub 2013 Apr 17. Cancer Immunol Immunother. 2013. PMID: 23591978 Free PMC article.
Severe adverse immunologic reaction in a patient with glioblastoma receiving autologous dendritic cell vaccines combined with GM-CSF and dose-intensified temozolomide.
Mitchell DA, Sayour EJ, Reap E, Schmittling R, DeLeon G, Norberg P, Desjardins A, Friedman AH, Friedman HS, Archer G, Sampson JH. Mitchell DA, et al. Cancer Immunol Res. 2015 Apr;3(4):320-5. doi: 10.1158/2326-6066.CIR-14-0100. Epub 2014 Nov 11. Cancer Immunol Res. 2015. PMID: 25387895 Free PMC article.
Vaccination strategies for neuro-oncology.
Sampson JH, Mitchell DA. Sampson JH, et al. Among authors: mitchell da. Neuro Oncol. 2015 Nov;17 Suppl 7(Suppl 7):vii15-vii25. doi: 10.1093/neuonc/nov159. Neuro Oncol. 2015. PMID: 26516221 Free PMC article. Review.
587 results