Tsai LH - Search Results

1

Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune function.

Akay LA, Effenberger AH, Tsai LH. Akay LA, et al. Among authors: tsai lh. Genes Dev. 2021 Feb 1;35(3-4):180-198. doi: 10.1101/gad.344218.120. Genes Dev. 2021. PMID: 33526585 Free PMC article. Review.

2

ASPM regulates Wnt signaling pathway activity in the developing brain.

Buchman JJ, Durak O, Tsai LH. Buchman JJ, et al. Among authors: tsai lh. Genes Dev. 2011 Sep 15;25(18):1909-14. doi: 10.1101/gad.16830211. Genes Dev. 2011. PMID: 21937711 Free PMC article.

3

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

Murn J, Zarnack K, Yang YJ, Durak O, Murphy EA, Cheloufi S, Gonzalez DM, Teplova M, Curk T, Zuber J, Patel DJ, Ule J, Luscombe NM, Tsai LH, Walsh CA, Shi Y. Murn J, et al. Among authors: tsai lh. Genes Dev. 2015 Mar 1;29(5):501-12. doi: 10.1101/gad.258483.115. Genes Dev. 2015. PMID: 25737280 Free PMC article.

4

Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.

Blanchard JW, Bula M, Davila-Velderrain J, Akay LA, Zhu L, Frank A, Victor MB, Bonner JM, Mathys H, Lin YT, Ko T, Bennett DA, Cam HP, Kellis M, Tsai LH. Blanchard JW, et al. Among authors: tsai lh. Nat Med. 2020 Jun;26(6):952-963. doi: 10.1038/s41591-020-0886-4. Epub 2020 Jun 8. Nat Med. 2020. PMID: 32514169 Free PMC article.

5

PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4.

Narayan P, Sienski G, Bonner JM, Lin YT, Seo J, Baru V, Haque A, Milo B, Akay LA, Graziosi A, Freyzon Y, Landgraf D, Hesse WR, Valastyan J, Barrasa MI, Tsai LH, Lindquist S. Narayan P, et al. Among authors: tsai lh. Cell Rep. 2020 Oct 6;33(1):108224. doi: 10.1016/j.celrep.2020.108224. Cell Rep. 2020. PMID: 33027662 Free PMC article.

6

Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.

Morshed N, Ralvenius WT, Nott A, Watson LA, Rodriguez FH, Akay LA, Joughin BA, Pao PC, Penney J, LaRocque L, Mastroeni D, Tsai LH, White FM. Morshed N, et al. Among authors: tsai lh. Mol Syst Biol. 2020 Dec;16(12):e9819. doi: 10.15252/msb.20209819. Mol Syst Biol. 2020. PMID: 33289969 Free PMC article.

7

Author Correction: Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.

Blanchard JW, Bula M, Davila-Velderrain J, Akay LA, Zhu L, Frank A, Victor MB, Bonner JM, Mathys H, Lin YT, Ko T, Bennett DA, Cam HP, Kellis M, Tsai LH. Blanchard JW, et al. Among authors: tsai lh. Nat Med. 2021 Feb;27(2):356. doi: 10.1038/s41591-021-01250-8. Nat Med. 2021. PMID: 33514950 No abstract available.

8

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia.

Sienski G, Narayan P, Bonner JM, Kory N, Boland S, Arczewska AA, Ralvenius WT, Akay L, Lockshin E, He L, Milo B, Graziosi A, Baru V, Lewis CA, Kellis M, Sabatini DM, Tsai LH, Lindquist S. Sienski G, et al. Among authors: tsai lh. Sci Transl Med. 2021 Mar 3;13(583):eaaz4564. doi: 10.1126/scitranslmed.aaz4564. Sci Transl Med. 2021. PMID: 33658354 Free PMC article.

9

Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity.

Victor MB, Leary N, Luna X, Meharena HS, Scannail AN, Bozzelli PL, Samaan G, Murdock MH, von Maydell D, Effenberger AH, Cerit O, Wen HL, Liu L, Welch G, Bonner M, Tsai LH. Victor MB, et al. Among authors: tsai lh. Cell Stem Cell. 2022 Aug 4;29(8):1197-1212.e8. doi: 10.1016/j.stem.2022.07.005. Cell Stem Cell. 2022. PMID: 35931030 Free PMC article.

10

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.

Blanchard JW, Akay LA, Davila-Velderrain J, von Maydell D, Mathys H, Davidson SM, Effenberger A, Chen CY, Maner-Smith K, Hajjar I, Ortlund EA, Bula M, Agbas E, Ng A, Jiang X, Kahn M, Blanco-Duque C, Lavoie N, Liu L, Reyes R, Lin YT, Ko T, R'Bibo L, Ralvenius WT, Bennett DA, Cam HP, Kellis M, Tsai LH. Blanchard JW, et al. Among authors: tsai lh. Nature. 2022 Nov;611(7937):769-779. doi: 10.1038/s41586-022-05439-w. Epub 2022 Nov 16. Nature. 2022. PMID: 36385529 Free PMC article.

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