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Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to stalk epitopes.
Freyn AW, Han J, Guthmiller JJ, Bailey MJ, Neu K, Turner HL, Rosado VC, Chromikova V, Huang M, Strohmeier S, Liu STH, Simon V, Krammer F, Ward AB, Palese P, Wilson PC, Nachbagauer R. Freyn AW, et al. Among authors: ward ab. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2018102118. doi: 10.1073/pnas.2018102118. Proc Natl Acad Sci U S A. 2021. PMID: 33593910 Free PMC article.
Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Laursen NS, Friesen RHE, Zhu X, Jongeneelen M, Blokland S, Vermond J, van Eijgen A, Tang C, van Diepen H, Obmolova G, van der Neut Kolfschoten M, Zuijdgeest D, Straetemans R, Hoffman RMB, Nieusma T, Pallesen J, Turner HL, Bernard SM, Ward AB, Luo J, Poon LLM, Tretiakova AP, Wilson JM, Limberis MP, Vogels R, Brandenburg B, Kolkman JA, Wilson IA. Laursen NS, et al. Among authors: ward ab. Science. 2018 Nov 2;362(6414):598-602. doi: 10.1126/science.aaq0620. Science. 2018. PMID: 30385580 Free PMC article.
HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite.
Nogal B, McCoy LE, van Gils MJ, Cottrell CA, Voss JE, Andrabi R, Pauthner M, Liang CH, Messmer T, Nedellec R, Shin M, Turner HL, Ozorowski G, Sanders RW, Burton DR, Ward AB. Nogal B, et al. Among authors: ward ab. Sci Adv. 2020 Jun 5;6(23):eaba0512. doi: 10.1126/sciadv.aba0512. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32548265 Free PMC article.
Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans.
Ellebedy AH, Nachbagauer R, Jackson KJL, Dai YN, Han J, Alsoussi WB, Davis CW, Stadlbauer D, Rouphael N, Chromikova V, McCausland M, Chang CY, Cortese M, Bower M, Chennareddy C, Schmitz AJ, Zarnitsyna VI, Lai L, Rajabhathor A, Kazemian C, Antia R, Mulligan MJ, Ward AB, Fremont DH, Boyd SD, Pulendran B, Krammer F, Ahmed R. Ellebedy AH, et al. Among authors: ward ab. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17957-17964. doi: 10.1073/pnas.1906613117. Epub 2020 Jul 13. Proc Natl Acad Sci U S A. 2020. PMID: 32661157 Free PMC article.
Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Antanasijevic A, Ueda G, Brouwer PJM, Copps J, Huang D, Allen JD, Cottrell CA, Yasmeen A, Sewall LM, Bontjer I, Ketas TJ, Turner HL, Berndsen ZT, Montefiori DC, Klasse PJ, Crispin M, Nemazee D, Moore JP, Sanders RW, King NP, Baker D, Ward AB. Antanasijevic A, et al. Among authors: ward ab. PLoS Pathog. 2020 Aug 11;16(8):e1008665. doi: 10.1371/journal.ppat.1008665. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32780770 Free PMC article.
Human germinal centres engage memory and naive B cells after influenza vaccination.
Turner JS, Zhou JQ, Han J, Schmitz AJ, Rizk AA, Alsoussi WB, Lei T, Amor M, McIntire KM, Meade P, Strohmeier S, Brent RI, Richey ST, Haile A, Yang YR, Klebert MK, Suessen T, Teefey S, Presti RM, Krammer F, Kleinstein SH, Ward AB, Ellebedy AH. Turner JS, et al. Among authors: ward ab. Nature. 2020 Oct;586(7827):127-132. doi: 10.1038/s41586-020-2711-0. Epub 2020 Aug 31. Nature. 2020. PMID: 32866963 Free PMC article.
Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate.
Bangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X, Torres JL, Diedrich JK, Tian JH, Portnoff AD, Patel N, Massare MJ, Yates JR 3rd, Nemazee D, Paulson JC, Glenn G, Smith G, Ward AB. Bangaru S, et al. Among authors: ward ab. Science. 2020 Nov 27;370(6520):1089-1094. doi: 10.1126/science.abe1502. Epub 2020 Oct 20. Science. 2020. PMID: 33082295 Free PMC article.
471 results