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Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.
Colombo A, Dinkel L, Müller SA, Sebastian Monasor L, Schifferer M, Cantuti-Castelvetri L, König J, Vidatic L, Bremova-Ertl T, Lieberman AP, Hecimovic S, Simons M, Lichtenthaler SF, Strupp M, Schneider SA, Tahirovic S. Colombo A, et al. Among authors: hecimovic s. Nat Commun. 2021 Feb 24;12(1):1158. doi: 10.1038/s41467-021-21428-5. Nat Commun. 2021. PMID: 33627648 Free PMC article.
Niemann-Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the beta-secretase pathway.
Malnar M, Kosicek M, Mitterreiter S, Omerbasic D, Lichtenthaler SF, Goate A, Hecimovic S. Malnar M, et al. Among authors: hecimovic s. Biochim Biophys Acta. 2010 Jul-Aug;1802(7-8):682-91. doi: 10.1016/j.bbadis.2010.05.006. Epub 2010 May 20. Biochim Biophys Acta. 2010. PMID: 20493254 Free PMC article.
BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
Causevic M, Dominko K, Malnar M, Vidatic L, Cermak S, Pigoni M, Kuhn PH, Colombo A, Havas D, Flunkert S, McDonald J, Gunnersen JM, Hutter-Paier B, Tahirovic S, Windisch M, Krainc D, Lichtenthaler SF, Hecimovic S. Causevic M, et al. Among authors: hecimovic s. PLoS One. 2018 Jul 6;13(7):e0200344. doi: 10.1371/journal.pone.0200344. eCollection 2018. PLoS One. 2018. PMID: 29979789 Free PMC article.
Emerging Trends in the Field of Inflammation and Proteinopathy in ALS/FTD Spectrum Disorder.
De Marchi F, Franjkic T, Schito P, Russo T, Nimac J, Chami AA, Mele A, Vidatic L, Kriz J, Julien JP, Apic G, Russell RB, Rogelj B, Cannon JR, Baralle M, Agosta F, Hecimovic S, Mazzini L, Buratti E, Munitic I. De Marchi F, et al. Among authors: hecimovic s. Biomedicines. 2023 May 31;11(6):1599. doi: 10.3390/biomedicines11061599. Biomedicines. 2023. PMID: 37371694 Free PMC article. Review.
Overlapping Neuroimmune Mechanisms and Therapeutic Targets in Neurodegenerative Disorders.
De Marchi F, Munitic I, Vidatic L, Papić E, Rački V, Nimac J, Jurak I, Novotni G, Rogelj B, Vuletic V, Liscic RM, Cannon JR, Buratti E, Mazzini L, Hecimovic S. De Marchi F, et al. Among authors: hecimovic s. Biomedicines. 2023 Oct 14;11(10):2793. doi: 10.3390/biomedicines11102793. Biomedicines. 2023. PMID: 37893165 Free PMC article. Review.
44 results