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Targeting a neoantigen derived from a common TP53 mutation.
Hsiue EH, Wright KM, Douglass J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, Liu Q, Watson E, Li Y, Pardoll DM, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Gabelli SB, Zhou S. Hsiue EH, et al. Among authors: gabelli sb. Science. 2021 Mar 5;371(6533):eabc8697. doi: 10.1126/science.abc8697. Epub 2021 Mar 1. Science. 2021. PMID: 33649166 Free PMC article.
Structural comparisons of class I phosphoinositide 3-kinases.
Amzel LM, Huang CH, Mandelker D, Lengauer C, Gabelli SB, Vogelstein B. Amzel LM, et al. Among authors: gabelli sb. Nat Rev Cancer. 2008 Sep;8(9):665-9. doi: 10.1038/nrc2443. Nat Rev Cancer. 2008. PMID: 18633356 Free PMC article. Review.
Structural effects of oncogenic PI3Kα mutations.
Gabelli SB, Huang CH, Mandelker D, Schmidt-Kittler O, Vogelstein B, Amzel LM. Gabelli SB, et al. Curr Top Microbiol Immunol. 2010;347:43-53. doi: 10.1007/82_2010_53. Curr Top Microbiol Immunol. 2010. PMID: 20593314 Free PMC article. Review.
PI3Kα inhibitors that inhibit metastasis.
Schmidt-Kittler O, Zhu J, Yang J, Liu G, Hendricks W, Lengauer C, Gabelli SB, Kinzler KW, Vogelstein B, Huso DL, Zhou S. Schmidt-Kittler O, et al. Among authors: gabelli sb. Oncotarget. 2010 Sep;1(5):339-48. doi: 10.18632/oncotarget.166. Oncotarget. 2010. PMID: 21179398 Free PMC article.
Structural basis of nSH2 regulation and lipid binding in PI3Kα.
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Miller MS, et al. Among authors: gabelli sb. Oncotarget. 2014 Jul 30;5(14):5198-208. doi: 10.18632/oncotarget.2263. Oncotarget. 2014. PMID: 25105564 Free PMC article.
104 results