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HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations.
Fazal R, Boeynaems S, Swijsen A, De Decker M, Fumagalli L, Moisse M, Vanneste J, Guo W, Boon R, Vercruysse T, Eggermont K, Swinnen B, Beckers J, Pakravan D, Vandoorne T, Vanden Berghe P, Verfaillie C, Van Den Bosch L, Van Damme P. Fazal R, et al. Among authors: van damme p, van den bosch l. EMBO J. 2021 Apr 1;40(7):e106177. doi: 10.15252/embj.2020106177. Epub 2021 Mar 10. EMBO J. 2021. PMID: 33694180 Free PMC article.
An alpha-mercaptoacrylic acid derivative (PD150606) inhibits selective motor neuron death via inhibition of kainate-induced Ca2+ influx and not via calpain inhibition.
Van den Bosch L, Van Damme P, Vleminckx V, Van Houtte E, Lemmens G, Missiaen L, Callewaert G, Robberecht W. Van den Bosch L, et al. Among authors: van damme p, van houtte e. Neuropharmacology. 2002 Apr;42(5):706-13. doi: 10.1016/s0028-3908(02)00010-2. Neuropharmacology. 2002. PMID: 11985829
Upregulation of HSP27 in a transgenic model of ALS.
Vleminckx V, Van Damme P, Goffin K, Delye H, Van Den Bosch L, Robberecht W. Vleminckx V, et al. Among authors: van damme p, van den bosch l. J Neuropathol Exp Neurol. 2002 Nov;61(11):968-74. doi: 10.1093/jnen/61.11.968. J Neuropathol Exp Neurol. 2002. PMID: 12430713
Long-lasting changes in GABA responsiveness in cultured neurons.
Chabwine JN, Van Damme P, Eggermont J, De Smedt H, Missiaen L, Van Den Bosch L, Parys JB, Robberecht W, Callewaert G. Chabwine JN, et al. Among authors: van damme p, van den bosch l. Neurosci Lett. 2004 Jul 15;365(1):69-72. doi: 10.1016/j.neulet.2004.04.049. Neurosci Lett. 2004. PMID: 15234475
317 results