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Page 1
The effect of spike mutations on SARS-CoV-2 neutralization.
Rees-Spear C, Muir L, Griffith SA, Heaney J, Aldon Y, Snitselaar JL, Thomas P, Graham C, Seow J, Lee N, Rosa A, Roustan C, Houlihan CF, Sanders RW, Gupta RK, Cherepanov P, Stauss HJ, Nastouli E; SAFER Investigators; Doores KJ, van Gils MJ, McCoy LE. Rees-Spear C, et al. Among authors: doores kj. Cell Rep. 2021 Mar 23;34(12):108890. doi: 10.1016/j.celrep.2021.108890. Epub 2021 Mar 6. Cell Rep. 2021. PMID: 33713594 Free PMC article.
Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers.
Falkowska E, Le KM, Ramos A, Doores KJ, Lee JH, Blattner C, Ramirez A, Derking R, van Gils MJ, Liang CH, Mcbride R, von Bredow B, Shivatare SS, Wu CY, Chan-Hui PY, Liu Y, Feizi T, Zwick MB, Koff WC, Seaman MS, Swiderek K, Moore JP, Evans D, Paulson JC, Wong CH, Ward AB, Wilson IA, Sanders RW, Poignard P, Burton DR. Falkowska E, et al. Among authors: doores kj. Immunity. 2014 May 15;40(5):657-68. doi: 10.1016/j.immuni.2014.04.009. Epub 2014 Apr 24. Immunity. 2014. PMID: 24768347 Free PMC article.
Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers.
Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe R, Kim HJ, Sanders RW, Doores KJ, Burton DR, Wilson IA, Ward AB, Moore JP, Crispin M. Pritchard LK, et al. Among authors: doores kj. Cell Rep. 2015 Jun 16;11(10):1604-13. doi: 10.1016/j.celrep.2015.05.017. Epub 2015 Jun 4. Cell Rep. 2015. PMID: 26051934 Free PMC article.
Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies.
McCoy LE, Falkowska E, Doores KJ, Le K, Sok D, van Gils MJ, Euler Z, Burger JA, Seaman MS, Sanders RW, Schuitemaker H, Poignard P, Wrin T, Burton DR. McCoy LE, et al. Among authors: doores kj. PLoS Pathog. 2015 Aug 12;11(8):e1005110. doi: 10.1371/journal.ppat.1005110. eCollection 2015 Aug. PLoS Pathog. 2015. PMID: 26267277 Free PMC article.
Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein.
Behrens AJ, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N, Seabright GE, Kramer HB, Spencer DI, Royle L, Lee JH, Klasse PJ, Burton DR, Wilson IA, Ward AB, Sanders RW, Moore JP, Doores KJ, Crispin M. Behrens AJ, et al. Among authors: doores kj. Cell Rep. 2016 Mar 22;14(11):2695-706. doi: 10.1016/j.celrep.2016.02.058. Epub 2016 Mar 10. Cell Rep. 2016. PMID: 26972002 Free PMC article.
A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus.
Allen ER, Krumm SA, Raghwani J, Halldorsson S, Elliott A, Graham VA, Koudriakova E, Harlos K, Wright D, Warimwe GM, Brennan B, Huiskonen JT, Dowall SD, Elliott RM, Pybus OG, Burton DR, Hewson R, Doores KJ, Bowden TA. Allen ER, et al. Among authors: doores kj. Cell Rep. 2018 Dec 26;25(13):3750-3758.e4. doi: 10.1016/j.celrep.2018.12.001. Cell Rep. 2018. PMID: 30590046 Free PMC article.
A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex.
Avanzato VA, Oguntuyo KY, Escalera-Zamudio M, Gutierrez B, Golden M, Kosakovsky Pond SL, Pryce R, Walter TS, Seow J, Doores KJ, Pybus OG, Munster VJ, Lee B, Bowden TA. Avanzato VA, et al. Among authors: doores kj. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25057-25067. doi: 10.1073/pnas.1912503116. Epub 2019 Nov 25. Proc Natl Acad Sci U S A. 2019. PMID: 31767754 Free PMC article.
Real-world evaluation of a novel technology for quantitative simultaneous antibody detection against multiple SARS-CoV-2 antigens in a cohort of patients presenting with COVID-19 syndrome.
Shaw AM, Hyde C, Merrick B, James-Pemberton P, Squires BK, Olkhov RV, Batra R, Patel A, Bisnauthsing K, Nebbia G, MacMahon E, Douthwaite S, Malim M, Neil S, Martinez Nunez R, Doores K, Mark TKI, Signell AW, Betancor G, Wilson HD, Galão RP, Pickering S, Edgeworth JD. Shaw AM, et al. Analyst. 2020 Aug 21;145(16):5638-5646. doi: 10.1039/d0an01066a. Epub 2020 Jul 8. Analyst. 2020. PMID: 32638712 Free PMC article.
A dynamic COVID-19 immune signature includes associations with poor prognosis.
Laing AG, Lorenc A, Del Molino Del Barrio I, Das A, Fish M, Monin L, Muñoz-Ruiz M, McKenzie DR, Hayday TS, Francos-Quijorna I, Kamdar S, Joseph M, Davies D, Davis R, Jennings A, Zlatareva I, Vantourout P, Wu Y, Sofra V, Cano F, Greco M, Theodoridis E, Freedman JD, Gee S, Chan JNE, Ryan S, Bugallo-Blanco E, Peterson P, Kisand K, Haljasmägi L, Chadli L, Moingeon P, Martinez L, Merrick B, Bisnauthsing K, Brooks K, Ibrahim MAA, Mason J, Lopez Gomez F, Babalola K, Abdul-Jawad S, Cason J, Mant C, Seow J, Graham C, Doores KJ, Di Rosa F, Edgeworth J, Shankar-Hari M, Hayday AC. Laing AG, et al. Among authors: doores kj. Nat Med. 2020 Oct;26(10):1623-1635. doi: 10.1038/s41591-020-1038-6. Epub 2020 Aug 17. Nat Med. 2020. PMID: 32807934
114 results