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Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice.
Keller A, Westenberger A, Sobrido MJ, García-Murias M, Domingo A, Sears RL, Lemos RR, Ordoñez-Ugalde A, Nicolas G, da Cunha JE, Rushing EJ, Hugelshofer M, Wurnig MC, Kaech A, Reimann R, Lohmann K, Dobričić V, Carracedo A, Petrović I, Miyasaki JM, Abakumova I, Mäe MA, Raschperger E, Zatz M, Zschiedrich K, Klepper J, Spiteri E, Prieto JM, Navas I, Preuss M, Dering C, Janković M, Paucar M, Svenningsson P, Saliminejad K, Khorshid HR, Novaković I, Aguzzi A, Boss A, Le Ber I, Defer G, Hannequin D, Kostić VS, Campion D, Geschwind DH, Coppola G, Betsholtz C, Klein C, Oliveira JR. Keller A, et al. Among authors: aguzzi a. Nat Genet. 2013 Sep;45(9):1077-82. doi: 10.1038/ng.2723. Epub 2013 Aug 4. Nat Genet. 2013. PMID: 23913003
A neuroprotective role for microglia in prion diseases.
Zhu C, Herrmann US, Falsig J, Abakumova I, Nuvolone M, Schwarz P, Frauenknecht K, Rushing EJ, Aguzzi A. Zhu C, et al. Among authors: aguzzi a. J Exp Med. 2016 May 30;213(6):1047-59. doi: 10.1084/jem.20151000. Epub 2016 May 16. J Exp Med. 2016. PMID: 27185853 Free PMC article.
Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis.
Seredenina T, Nayernia Z, Sorce S, Maghzal GJ, Filippova A, Ling SC, Basset O, Plastre O, Daali Y, Rushing EJ, Giordana MT, Cleveland DW, Aguzzi A, Stocker R, Krause KH, Jaquet V. Seredenina T, et al. Among authors: aguzzi a. Free Radic Biol Med. 2016 Aug;97:95-108. doi: 10.1016/j.freeradbiomed.2016.05.016. Epub 2016 May 19. Free Radic Biol Med. 2016. PMID: 27212019 Free article.
Cystatin F is a biomarker of prion pathogenesis in mice.
Nuvolone M, Schmid N, Miele G, Sorce S, Moos R, Schori C, Beerli RR, Bauer M, Saudan P, Dietmeier K, Lachmann I, Linnebank M, Martin R, Kallweit U, Kana V, Rushing EJ, Budka H, Aguzzi A. Nuvolone M, et al. Among authors: aguzzi a. PLoS One. 2017 Feb 8;12(2):e0171923. doi: 10.1371/journal.pone.0171923. eCollection 2017. PLoS One. 2017. PMID: 28178353 Free PMC article.
Regulated expression of amyloidogenic immunoglobulin light chains in mice.
Nuvolone M, Sorce S, Pelczar P, Rushing E, Lavatelli F, Rognoni P, Valentini V, Palladini G, Merlini G, Aguzzi A. Nuvolone M, et al. Among authors: aguzzi a. Amyloid. 2017 Mar;24(sup1):52-53. doi: 10.1080/13506129.2017.1289914. Amyloid. 2017. PMID: 28434289 No abstract available.
Prion pathogenesis is unaltered in a mouse strain with a permeable blood-brain barrier.
Keller A, Nuvolone M, Abakumova I, Chincisan A, Reimann R, Avar M, Heinzer D, Hornemann S, Wagner J, Kirschenbaum D, Voigt FF, Zhu C, Regli L, Helmchen F, Aguzzi A. Keller A, et al. Among authors: aguzzi a. PLoS Pathog. 2018 Nov 29;14(11):e1007424. doi: 10.1371/journal.ppat.1007424. eCollection 2018 Nov. PLoS Pathog. 2018. PMID: 30496289 Free PMC article.
641 results