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Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer.
Mehta AK, Cheney EM, Hartl CA, Pantelidou C, Oliwa M, Castrillon JA, Lin JR, Hurst KE, de Oliveira Taveira M, Johnson NT, Oldham WM, Kalocsay M, Berberich MJ, Boswell SA, Kothari A, Johnson S, Dillon DA, Lipschitz M, Rodig S, Santagata S, Garber JE, Tung N, Yélamos J, Thaxton JE, Mittendorf EA, Sorger PK, Shapiro GI, Guerriero JL. Mehta AK, et al. Among authors: hurst ke. Nat Cancer. 2021 Jan;2(1):66-82. doi: 10.1038/s43018-020-00148-7. Epub 2020 Dec 14. Nat Cancer. 2021. PMID: 33738458 Free PMC article.
Remodeling Translation Primes CD8+ T-cell Antitumor Immunity.
Hurst KE, Lawrence KA, Robino RA, Ball LE, Chung D, Thaxton JE. Hurst KE, et al. Cancer Immunol Res. 2020 May;8(5):587-595. doi: 10.1158/2326-6066.CIR-19-0516. Epub 2020 Feb 19. Cancer Immunol Res. 2020. PMID: 32075802
Stress-Mediated Attenuation of Translation Undermines T-cell Activity in Cancer.
Riesenberg BP, Hunt EG, Tennant MD, Hurst KE, Andrews AM, Leddy LR, Neskey DM, Hill EG, Rivera GOR, Paulos CM, Gao P, Thaxton JE. Riesenberg BP, et al. Among authors: hurst ke. Cancer Res. 2022 Dec 2;82(23):4386-4399. doi: 10.1158/0008-5472.CAN-22-1744. Cancer Res. 2022. PMID: 36126165 Free PMC article.
Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment.
Hunt EG, Hurst KE, Riesenberg BP, Kennedy AS, Gandy EJ, Andrews AM, Del Mar Alicea Pauneto C, Ball LE, Wallace ED, Gao P, Meier J, Serody JJ, Coleman MF, Thaxton JE. Hunt EG, et al. Among authors: hurst ke. Cell Metab. 2024 May 7;36(5):969-983.e10. doi: 10.1016/j.cmet.2024.02.009. Epub 2024 Mar 14. Cell Metab. 2024. PMID: 38490211 Free article.
High-Fat Diet Drives an Aggressive Pancreatic Cancer Phenotype.
Garcia DI, Hurst KE, Bradshaw A, Janakiraman H, Wang C, Camp ER. Garcia DI, et al. Among authors: hurst ke. J Surg Res. 2021 Aug;264:163-172. doi: 10.1016/j.jss.2020.10.007. Epub 2021 Apr 7. J Surg Res. 2021. PMID: 33838401
Densified HKUST-1 Monoliths as a Route to High Volumetric and Gravimetric Hydrogen Storage Capacity.
Madden DG, O'Nolan D, Rampal N, Babu R, Çamur C, Al Shakhs AN, Zhang SY, Rance GA, Perez J, Maria Casati NP, Cuadrado-Collados C, O'Sullivan D, Rice NP, Gennett T, Parilla P, Shulda S, Hurst KE, Stavila V, Allendorf MD, Silvestre-Albero J, Forse AC, Champness NR, Chapman KW, Fairen-Jimenez D. Madden DG, et al. Among authors: hurst ke. J Am Chem Soc. 2022 Aug 3;144(30):13729-13739. doi: 10.1021/jacs.2c04608. Epub 2022 Jul 25. J Am Chem Soc. 2022. PMID: 35876689 Free PMC article.
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