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1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans.
Sønderby IE, van der Meer D, Moreau C, Kaufmann T, Walters GB, Ellegaard M, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn NB, Blangero J, Boomsma DI, Brodaty H, Brouwer RM, Bülow R, Bøen R, Cahn W, Calhoun VD, Caspers S, Ching CRK, Cichon S, Ciufolini S, Crespo-Facorro B, Curran JE, Dale AM, Dalvie S, Dazzan P, de Geus EJC, de Zubicaray GI, de Zwarte SMC, Desrivieres S, Doherty JL, Donohoe G, Draganski B, Ehrlich S, Eising E, Espeseth T, Fejgin K, Fisher SE, Fladby T, Frei O, Frouin V, Fukunaga M, Gareau T, Ge T, Glahn DC, Grabe HJ, Groenewold NA, Gústafsson Ó, Haavik J, Haberg AK, Hall J, Hashimoto R, Hehir-Kwa JY, Hibar DP, Hillegers MHJ, Hoffmann P, Holleran L, Holmes AJ, Homuth G, Hottenga JJ, Hulshoff Pol HE, Ikeda M, Jahanshad N, Jockwitz C, Johansson S, Jönsson EG, Jørgensen NR, Kikuchi M, Knowles EEM, Kumar K, Le Hellard S, Leu C, Linden DEJ, Liu J, Lundervold A, Lundervold AJ, Maillard AM, Martin NG, Martin-Brevet S, Mather KA, Mathias SR, McMahon KL, McRae AF, Medland SE, Meyer-Lindenberg A, Moberget T, Modenato C, Sánchez JM, Morris DW, Mühleisen TW, Murray RM, Nielsen J, Nordvik JE, Nyberg L, Loohuis LMO, Ophoff RA, Owen MJ, Pau… See abstract for full author list ➔ Sønderby IE, et al. Among authors: hibar dp. Transl Psychiatry. 2021 Mar 22;11(1):182. doi: 10.1038/s41398-021-01213-0. Transl Psychiatry. 2021. PMID: 33753722 Free PMC article.
Boosting power for clinical trials using classifiers based on multiple biomarkers.
Kohannim O, Hua X, Hibar DP, Lee S, Chou YY, Toga AW, Jack CR Jr, Weiner MW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Kohannim O, et al. Among authors: hibar dp. Neurobiol Aging. 2010 Aug;31(8):1429-42. doi: 10.1016/j.neurobiolaging.2010.04.022. Epub 2010 Jun 11. Neurobiol Aging. 2010. PMID: 20541286 Free PMC article. Clinical Trial.
Obesity is linked with lower brain volume in 700 AD and MCI patients.
Ho AJ, Raji CA, Becker JT, Lopez OL, Kuller LH, Hua X, Lee S, Hibar D, Dinov ID, Stein JL, Jack CR Jr, Weiner MW, Toga AW, Thompson PM; Cardiovascular Health Study; ADNI. Ho AJ, et al. Neurobiol Aging. 2010 Aug;31(8):1326-39. doi: 10.1016/j.neurobiolaging.2010.04.006. Epub 2010 Jun 8. Neurobiol Aging. 2010. PMID: 20570405 Free PMC article.
Sex and age differences in atrophic rates: an ADNI study with n=1368 MRI scans.
Hua X, Hibar DP, Lee S, Toga AW, Jack CR Jr, Weiner MW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Hua X, et al. Among authors: hibar dp. Neurobiol Aging. 2010 Aug;31(8):1463-80. doi: 10.1016/j.neurobiolaging.2010.04.033. Neurobiol Aging. 2010. PMID: 20620666 Free PMC article.
Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjects.
Hibar DP, Stein JL, Kohannim O, Jahanshad N, Saykin AJ, Shen L, Kim S, Pankratz N, Foroud T, Huentelman MJ, Potkin SG, Jack CR Jr, Weiner MW, Toga AW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Hibar DP, et al. Neuroimage. 2011 Jun 15;56(4):1875-91. doi: 10.1016/j.neuroimage.2011.03.077. Epub 2011 Apr 8. Neuroimage. 2011. PMID: 21497199 Free PMC article.
Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search.
Stein JL, Hibar DP, Madsen SK, Khamis M, McMahon KL, de Zubicaray GI, Hansell NK, Montgomery GW, Martin NG, Wright MJ, Saykin AJ, Jack CR Jr, Weiner MW, Toga AW, Thompson PM; Alzheimer’s Disease Neuroimaging Initiative Investigators. Stein JL, et al. Among authors: hibar dp. Mol Psychiatry. 2011 Sep;16(9):927-37, 881. doi: 10.1038/mp.2011.32. Epub 2011 Apr 19. Mol Psychiatry. 2011. PMID: 21502949 Free PMC article.
Hippocampal volume is related to body mass index in Alzheimer's disease.
Ho AJ, Raji CA, Saharan P, DeGiorgio A, Madsen SK, Hibar DP, Stein JL, Becker JT, Lopez OL, Toga AW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Ho AJ, et al. Among authors: hibar dp. Neuroreport. 2011 Jan 5;22(1):10-4. doi: 10.1097/wnr.0b013e3283412868. Neuroreport. 2011. PMID: 21539003 Free PMC article.
Brain structure in healthy adults is related to serum transferrin and the H63D polymorphism in the HFE gene.
Jahanshad N, Kohannim O, Hibar DP, Stein JL, McMahon KL, de Zubicaray GI, Medland SE, Montgomery GW, Whitfield JB, Martin NG, Wright MJ, Toga AW, Thompson PM. Jahanshad N, et al. Among authors: hibar dp. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):E851-9. doi: 10.1073/pnas.1105543109. Epub 2012 Jan 9. Proc Natl Acad Sci U S A. 2012. PMID: 22232660 Free PMC article.
Multilocus genetic analysis of brain images.
Hibar DP, Kohannim O, Stein JL, Chiang MC, Thompson PM. Hibar DP, et al. Front Genet. 2011 Oct 21;2:73. doi: 10.3389/fgene.2011.00073. eCollection 2011. Front Genet. 2011. PMID: 22303368 Free PMC article.
Identification of common variants associated with human hippocampal and intracranial volumes.
Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería ME,… See abstract for full author list ➔ Stein JL, et al. Among authors: hibar dp. Nat Genet. 2012 Apr 15;44(5):552-61. doi: 10.1038/ng.2250. Nat Genet. 2012. PMID: 22504417 Free PMC article.
118 results