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1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans.
Sønderby IE, van der Meer D, Moreau C, Kaufmann T, Walters GB, Ellegaard M, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn NB, Blangero J, Boomsma DI, Brodaty H, Brouwer RM, Bülow R, Bøen R, Cahn W, Calhoun VD, Caspers S, Ching CRK, Cichon S, Ciufolini S, Crespo-Facorro B, Curran JE, Dale AM, Dalvie S, Dazzan P, de Geus EJC, de Zubicaray GI, de Zwarte SMC, Desrivieres S, Doherty JL, Donohoe G, Draganski B, Ehrlich S, Eising E, Espeseth T, Fejgin K, Fisher SE, Fladby T, Frei O, Frouin V, Fukunaga M, Gareau T, Ge T, Glahn DC, Grabe HJ, Groenewold NA, Gústafsson Ó, Haavik J, Haberg AK, Hall J, Hashimoto R, Hehir-Kwa JY, Hibar DP, Hillegers MHJ, Hoffmann P, Holleran L, Holmes AJ, Homuth G, Hottenga JJ, Hulshoff Pol HE, Ikeda M, Jahanshad N, Jockwitz C, Johansson S, Jönsson EG, Jørgensen NR, Kikuchi M, Knowles EEM, Kumar K, Le Hellard S, Leu C, Linden DEJ, Liu J, Lundervold A, Lundervold AJ, Maillard AM, Martin NG, Martin-Brevet S, Mather KA, Mathias SR, McMahon KL, McRae AF, Medland SE, Meyer-Lindenberg A, Moberget T, Modenato C, Sánchez JM, Morris DW, Mühleisen TW, Murray RM, Nielsen J, Nordvik JE, Nyberg L, Loohuis LMO, Ophoff RA, Owen MJ, Pau… See abstract for full author list ➔ Sønderby IE, et al. Among authors: linden dej. Transl Psychiatry. 2021 Mar 22;11(1):182. doi: 10.1038/s41398-021-01213-0. Transl Psychiatry. 2021. PMID: 33753722 Free PMC article.
Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects.
Erk S, Meyer-Lindenberg A, Linden DEJ, Lancaster T, Mohnke S, Grimm O, Degenhardt F, Holmans P, Pocklington A, Schmierer P, Haddad L, Mühleisen TW, Mattheisen M, Witt SH, Romanczuk-Seiferth N, Tost H, Schott BH, Cichon S, Nöthen MM, Rietschel M, Heinz A, Walter H. Erk S, et al. Among authors: linden dej. Neuroimage. 2014 Jul 1;94:147-154. doi: 10.1016/j.neuroimage.2014.03.007. Epub 2014 Mar 16. Neuroimage. 2014. PMID: 24642287
Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: evidence from two independent cohorts.
Oertel-Knöchel V, Lancaster TM, Knöchel C, Stäblein M, Storchak H, Reinke B, Jurcoane A, Kniep J, Prvulovic D, Mantripragada K, Tansey KE, O'Donovan MC, Owen MJ, Linden DE. Oertel-Knöchel V, et al. Neuroimage Clin. 2015 Mar 13;7:764-70. doi: 10.1016/j.nicl.2015.03.005. eCollection 2015. Neuroimage Clin. 2015. PMID: 25844328 Free PMC article.
A national population-based e-cohort of people with psychosis (PsyCymru) linking prospectively ascertained phenotypically rich and genetic data to routinely collected records: overview, recruitment and linkage.
Lloyd K, McGregor J, John A, Craddock N, Walters JT, Linden D, Jones I, Bentall R, Lyons RA, Ford DV, Owen MJ. Lloyd K, et al. Schizophr Res. 2015 Aug;166(1-3):131-6. doi: 10.1016/j.schres.2015.05.036. Epub 2015 Jun 29. Schizophr Res. 2015. PMID: 26139629
Common alleles contribute to schizophrenia in CNV carriers.
Tansey KE, Rees E, Linden DE, Ripke S, Chambert KD, Moran JL, McCarroll SA, Holmans P, Kirov G, Walters J, Owen MJ, O'Donovan MC. Tansey KE, et al. Mol Psychiatry. 2016 Aug;21(8):1085-9. doi: 10.1038/mp.2015.143. Epub 2015 Sep 22. Mol Psychiatry. 2016. PMID: 26390827 Free PMC article.
346 results