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Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer.
Tello-Lafoz M, Srpan K, Sanchez EE, Hu J, Remsik J, Romin Y, Calò A, Hoen D, Bhanot U, Morris L, Boire A, Hsu KC, Massagué J, Huse M, Er EE. Tello-Lafoz M, et al. Among authors: boire a. Immunity. 2021 May 11;54(5):1037-1054.e7. doi: 10.1016/j.immuni.2021.02.020. Epub 2021 Mar 22. Immunity. 2021. PMID: 33756102 Free PMC article.
Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer.
Chen Q, Boire A, Jin X, Valiente M, Er EE, Lopez-Soto A, Jacob L, Patwa R, Shah H, Xu K, Cross JR, Massagué J. Chen Q, et al. Among authors: boire a. Nature. 2016 May 26;533(7604):493-498. doi: 10.1038/nature18268. Epub 2016 May 18. Nature. 2016. PMID: 27225120 Free PMC article.
Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines.
Valiente M, Van Swearingen AED, Anders CK, Bairoch A, Boire A, Bos PD, Cittelly DM, Erez N, Ferraro GB, Fukumura D, Gril B, Herlyn M, Holmen SL, Jain RK, Joyce JA, Lorger M, Massague J, Neman J, Sibson NR, Steeg PS, Thorsen F, Young LS, Varešlija D, Vultur A, Weis-Garcia F, Winkler F. Valiente M, et al. Among authors: boire a. Cancer Res. 2020 Oct 15;80(20):4314-4323. doi: 10.1158/0008-5472.CAN-20-0291. Epub 2020 Jul 8. Cancer Res. 2020. PMID: 32641416 Free PMC article. Review.
Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis.
Chi Y, Remsik J, Kiseliovas V, Derderian C, Sener U, Alghader M, Saadeh F, Nikishina K, Bale T, Iacobuzio-Donahue C, Thomas T, Pe'er D, Mazutis L, Boire A. Chi Y, et al. Among authors: boire a. Science. 2020 Jul 17;369(6501):276-282. doi: 10.1126/science.aaz2193. Science. 2020. PMID: 32675368 Free PMC article.
Leptomeningeal metastatic cells adopt two phenotypic states.
Remsik J, Chi Y, Tong X, Sener U, Derderian C, Park A, Saadeh F, Bale T, Boire A. Remsik J, et al. Among authors: boire a. Cancer Rep (Hoboken). 2022 Apr;5(4):e1236. doi: 10.1002/cnr2.1236. Epub 2020 Jan 29. Cancer Rep (Hoboken). 2022. PMID: 33372403 Free PMC article.
Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination.
Martirosian V, Deshpande K, Zhou H, Shen K, Smith K, Northcott P, Lin M, Stepanosyan V, Das D, Remsik J, Isakov D, Boire A, De Feyter H, Hurth K, Li S, Wiemels J, Nakamura B, Shao L, Danilov C, Chen T, Neman J. Martirosian V, et al. Among authors: boire a. Cell Rep. 2021 Jun 29;35(13):109302. doi: 10.1016/j.celrep.2021.109302. Cell Rep. 2021. PMID: 34192534 Free PMC article.
83 results