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Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer.
Immunity. 2021 May 11;54(5):1037-1054.e7. doi: 10.1016/j.immuni.2021.02.020. Epub 2021 Mar 22.
Immunity. 2021.
PMID: 33756102
Free PMC article.
Human Cytomegalovirus Infection Promotes Expansion of a Functionally Superior Cytoplasmic CD3+ NK Cell Subset with a Bcl11b-Regulated T Cell Signature.
Wu Z, Lau CM, Sottile R, Le Luduec JB, Panjwani MK, Conaty PM, Srpan K, Laib Sampaio K, Mertens T, Adler SP, Hill AB, Barker JN, Cheung NV, Sun JC, Hsu KC.
Wu Z, et al. Among authors: srpan k.
J Immunol. 2021 Nov 15;207(10):2534-2544. doi: 10.4049/jimmunol.2001319. Epub 2021 Oct 8.
J Immunol. 2021.
PMID: 34625521
Free PMC article.
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Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells.
Srpan K, Ambrose A, Karampatzakis A, Saeed M, Cartwright ANR, Guldevall K, De Matos GDSC, Önfelt B, Davis DM.
Srpan K, et al.
J Cell Biol. 2018 Sep 3;217(9):3267-3283. doi: 10.1083/jcb.201712085. Epub 2018 Jul 2.
J Cell Biol. 2018.
PMID: 29967280
Free PMC article.
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Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells.
Kolba MD, Dudka W, Zaręba-Kozioł M, Kominek A, Ronchi P, Turos L, Chroscicki P, Wlodarczyk J, Schwab Y, Klejman A, Cysewski D, Srpan K, Davis DM, Piwocka K.
Kolba MD, et al. Among authors: srpan k.
Cell Death Dis. 2019 Oct 28;10(11):817. doi: 10.1038/s41419-019-2045-8.
Cell Death Dis. 2019.
PMID: 31659149
Free PMC article.
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Fatty acid oxidation fuels natural killer cell responses against infection and cancer.
Sheppard S, Srpan K, Lin W, Lee M, Delconte RB, Owyong M, Carmeliet P, Davis DM, Xavier JB, Hsu KC, Sun JC.
Sheppard S, et al. Among authors: srpan k.
Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2319254121. doi: 10.1073/pnas.2319254121. Epub 2024 Mar 5.
Proc Natl Acad Sci U S A. 2024.
PMID: 38442180
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