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Promises and challenges of adoptive T-cell therapies for solid tumours.
Morotti M, Albukhari A, Alsaadi A, Artibani M, Brenton JD, Curbishley SM, Dong T, Dustin ML, Hu Z, McGranahan N, Miller ML, Santana-Gonzalez L, Seymour LW, Shi T, Van Loo P, Yau C, White H, Wietek N, Church DN, Wedge DC, Ahmed AA. Morotti M, et al. Among authors: dong t. Br J Cancer. 2021 May;124(11):1759-1776. doi: 10.1038/s41416-021-01353-6. Epub 2021 Mar 29. Br J Cancer. 2021. PMID: 33782566 Free PMC article. Review.
Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells.
Saliba DG, Céspedes-Donoso PF, Bálint Š, Compeer EB, Korobchevskaya K, Valvo S, Mayya V, Kvalvaag A, Peng Y, Dong T, Tognoli ML, O'Neill E, Bonham S, Fischer R, Kessler BM, Dustin ML. Saliba DG, et al. Among authors: dong t. Elife. 2019 Aug 30;8:e47528. doi: 10.7554/eLife.47528. Elife. 2019. PMID: 31469364 Free PMC article.
Self-Maintaining CD103+ Cancer-Specific T Cells Are Highly Energetic with Rapid Cytotoxic and Effector Responses.
Abd Hamid M, Colin-York H, Khalid-Alham N, Browne M, Cerundolo L, Chen JL, Yao X, Rosendo-Machado S, Waugh C, Maldonado-Perez D, Bowes E, Verrill C, Cerundolo V, Conlon CP, Fritzsche M, Peng Y, Dong T. Abd Hamid M, et al. Among authors: dong t. Cancer Immunol Res. 2020 Feb;8(2):203-216. doi: 10.1158/2326-6066.CIR-19-0554. Epub 2019 Nov 26. Cancer Immunol Res. 2020. PMID: 31771983 Free PMC article.
Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse.
Felce JH, Parolini L, Sezgin E, Céspedes PF, Korobchevskaya K, Jones M, Peng Y, Dong T, Fritzsche M, Aarts D, Frater J, Dustin ML. Felce JH, et al. Among authors: dong t. Front Cell Dev Biol. 2021 Jan 18;8:608484. doi: 10.3389/fcell.2020.608484. eCollection 2020. Front Cell Dev Biol. 2021. PMID: 33537301 Free PMC article.
T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles.
Céspedes PF, Jainarayanan A, Fernández-Messina L, Valvo S, Saliba DG, Kurz E, Kvalvaag A, Chen L, Ganskow C, Colin-York H, Fritzsche M, Peng Y, Dong T, Johnson E, Siller-Farfán JA, Dushek O, Sezgin E, Peacock B, Law A, Aubert D, Engledow S, Attar M, Hester S, Fischer R, Sánchez-Madrid F, Dustin ML. Céspedes PF, et al. Among authors: dong t. Nat Commun. 2022 Jun 16;13(1):3460. doi: 10.1038/s41467-022-31160-3. Nat Commun. 2022. PMID: 35710644 Free PMC article.
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.
Hamid MHBA, Cespedes PF, Jin C, Chen JL, Gileadi U, Antoun E, Liang Z, Gao F, Teague R, Manoharan N, Maldonado-Perez D, Khalid-Alham N, Cerundolo L, Ciaoca R, Hester SS, Pinto-Fernández A, Draganov SD, Vendrell I, Liu G, Yao X, Kvalvaag A, Dominey-Foy DCC, Nanayakkara C, Kanellakis N, Chen YL, Waugh C, Clark SA, Clark K, Sopp P, Rahman NM, Verrill C, Kessler BM, Ogg G, Fernandes RA, Fisher R, Peng Y, Dustin ML, Dong T. Hamid MHBA, et al. Among authors: dong t. Nat Immunol. 2024 May;25(5):834-846. doi: 10.1038/s41590-024-01802-3. Epub 2024 Apr 1. Nat Immunol. 2024. PMID: 38561495 Free PMC article.
Enriched HLA-E and CD94/NKG2A Interaction Limits Antitumor CD8+ Tumor-Infiltrating T Lymphocyte Responses.
Abd Hamid M, Wang RZ, Yao X, Fan P, Li X, Chang XM, Feng Y, Jones S, Maldonado-Perez D, Waugh C, Verrill C, Simmons A, Cerundolo V, McMichael A, Conlon C, Wang X, Peng Y, Dong T. Abd Hamid M, et al. Among authors: dong t. Cancer Immunol Res. 2019 Aug;7(8):1293-1306. doi: 10.1158/2326-6066.CIR-18-0885. Epub 2019 Jun 18. Cancer Immunol Res. 2019. PMID: 31213473
2,419 results