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Page 1
Use of placebos in Phase 1 preventive HIV vaccine clinical trials.
Huang Y, Karuna ST, Janes H, Frahm N, Nason M, Edlefsen PT, Kublin JG, Corey L, McElrath MJ, Gilbert PB. Huang Y, et al. Among authors: edlefsen pt. Vaccine. 2015 Feb 4;33(6):749-52. doi: 10.1016/j.vaccine.2014.10.017. Epub 2014 Oct 23. Vaccine. 2015. PMID: 25454855 Free PMC article.
Transmitted/Founder HIV-1 Subtype C Viruses Show Distinctive Signature Patterns in Vif, Vpr, and Vpu That Are Under Subsequent Immune Pressure During Early Infection.
Rossenkhan R, MacLeod IJ, Brumme ZL, Magaret CA, Sebunya TK, Musonda R, Gashe BA, Edlefsen PT, Novitsky V, Essex M. Rossenkhan R, et al. Among authors: edlefsen pt. AIDS Res Hum Retroviruses. 2016 Oct/Nov;32(10-11):1031-1045. doi: 10.1089/AID.2015.0330. Epub 2016 Jul 26. AIDS Res Hum Retroviruses. 2016. PMID: 27349335 Free PMC article.
Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120.
deCamp AC, Rolland M, Edlefsen PT, Sanders-Buell E, Hall B, Magaret CA, Fiore-Gartland AJ, Juraska M, Carpp LN, Karuna ST, Bose M, LePore S, Miller S, O'Sullivan A, Poltavee K, Bai H, Dommaraju K, Zhao H, Wong K, Chen L, Ahmed H, Goodman D, Tay MZ, Gottardo R, Koup RA, Bailer R, Mascola JR, Graham BS, Roederer M, O'Connell RJ, Michael NL, Robb ML, Adams E, D'Souza P, Kublin J, Corey L, Geraghty DE, Frahm N, Tomaras GD, McElrath MJ, Frenkel L, Styrchak S, Tovanabutra S, Sobieszczyk ME, Hammer SM, Kim JH, Mullins JI, Gilbert PB. deCamp AC, et al. Among authors: edlefsen pt. PLoS One. 2017 Nov 17;12(11):e0185959. doi: 10.1371/journal.pone.0185959. eCollection 2017. PLoS One. 2017. PMID: 29149197 Free PMC article.
Combining Viral Genetics and Statistical Modeling to Improve HIV-1 Time-of-infection Estimation towards Enhanced Vaccine Efficacy Assessment.
Rossenkhan R, Rolland M, Labuschagne JPL, Ferreira RC, Magaret CA, Carpp LN, Matsen Iv FA, Huang Y, Rudnicki EE, Zhang Y, Ndabambi N, Logan M, Holzman T, Abrahams MR, Anthony C, Tovanabutra S, Warth C, Botha G, Matten D, Nitayaphan S, Kibuuka H, Sawe FK, Chopera D, Eller LA, Travers S, Robb ML, Williamson C, Gilbert PB, Edlefsen PT. Rossenkhan R, et al. Among authors: edlefsen pt. Viruses. 2019 Jul 3;11(7):607. doi: 10.3390/v11070607. Viruses. 2019. PMID: 31277299 Free PMC article.
Molecular dating and viral load growth rates suggested that the eclipse phase lasted about a week in HIV-1 infected adults in East Africa and Thailand.
Rolland M, Tovanabutra S, Dearlove B, Li Y, Owen CL, Lewitus E, Sanders-Buell E, Bose M, O'Sullivan A, Rossenkhan R, Labuschagne JPL, Edlefsen PT, Reeves DB, Kijak G, Miller S, Poltavee K, Lee J, Bonar L, Harbolick E, Ahani B, Pham P, Kibuuka H, Maganga L, Nitayaphan S, Sawe FK, Eller LA, Gramzinski R, Kim JH, Michael NL, Robb ML; RV217 Study Team. Rolland M, et al. Among authors: edlefsen pt. PLoS Pathog. 2020 Feb 6;16(2):e1008179. doi: 10.1371/journal.ppat.1008179. eCollection 2020 Feb. PLoS Pathog. 2020. PMID: 32027734 Free PMC article. Clinical Trial.
Long-term mucosal T cell activation and homing phenotypes in recipients of an Ad5-vectored HIV vaccine.
Curlin ME, Shao J, Diaz G, Edlefsen PT, Novak RM, Mayer KH, Allen M, Morgan C, Maenza J, Buchbinder S, Keefer MC, Rosa SC, Corey L, Duerr A; NIAID HIV Vaccine Trials Network (HVTN). Curlin ME, et al. Among authors: edlefsen pt. Vaccine. 2020 Aug 10;38(36):5814-5821. doi: 10.1016/j.vaccine.2020.06.043. Epub 2020 Jul 14. Vaccine. 2020. PMID: 32680773 Free PMC article.
CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification.
Okoye AA, Duell DD, Fukazawa Y, Varco-Merth B, Marenco A, Behrens H, Chaunzwa M, Selseth AN, Gilbride RM, Shao J, Edlefsen PT, Geleziunas R, Pinkevych M, Davenport MP, Busman-Sahay K, Nekorchuk M, Park H, Smedley J, Axthelm MK, Estes JD, Hansen SG, Keele BF, Lifson JD, Picker LJ. Okoye AA, et al. Among authors: edlefsen pt. J Clin Invest. 2021 Apr 15;131(8):e141677. doi: 10.1172/JCI141677. J Clin Invest. 2021. PMID: 33630764 Free PMC article.
68 results