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Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.
Garcia G Jr, Sharma A, Ramaiah A, Sen C, Purkayastha A, Kohn DB, Parcells MS, Beck S, Kim H, Bakowski MA, Kirkpatrick MG, Riva L, Wolff KC, Han B, Yuen C, Ulmert D, Purbey PK, Scumpia P, Beutler N, Rogers TF, Chatterjee AK, Gabriel G, Bartenschlager R, Gomperts B, Svendsen CN, Betz UAK, Damoiseaux RD, Arumugaswami V. Garcia G Jr, et al. Among authors: gomperts b. Cell Rep. 2021 Apr 6;35(1):108940. doi: 10.1016/j.celrep.2021.108940. Epub 2021 Mar 18. Cell Rep. 2021. PMID: 33784499 Free PMC article.
Correction to: Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization.
Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. Hazim RA, et al. Among authors: gomperts bn. Stem Cell Res Ther. 2019 Feb 12;10(1):52. doi: 10.1186/s13287-019-1147-7. Stem Cell Res Ther. 2019. PMID: 30755264 Free PMC article.
Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule.
Vijayaraj P, Minasyan A, Durra A, Karumbayaram S, Mehrabi M, Aros CJ, Ahadome SD, Shia DW, Chung K, Sandlin JM, Darmawan KF, Bhatt KV, Manze CC, Paul MK, Wilkinson DC, Yan W, Clark AT, Rickabaugh TM, Wallace WD, Graeber TG, Damoiseaux R, Gomperts BN. Vijayaraj P, et al. Cell Rep. 2019 Dec 10;29(11):3488-3505.e9. doi: 10.1016/j.celrep.2019.11.019. Cell Rep. 2019. PMID: 31825831 Free PMC article.
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery.
Mulay A, Konda B, Garcia G Jr, Yao C, Beil S, Sen C, Purkayastha A, Kolls JK, Pociask DA, Pessina P, de Aja JS, Garcia-de-Alba C, Kim CF, Gomperts B, Arumugaswami V, Stripp BR. Mulay A, et al. Among authors: gomperts b. bioRxiv [Preprint]. 2020 Jun 29:2020.06.29.174623. doi: 10.1101/2020.06.29.174623. bioRxiv. 2020. PMID: 32637946 Free PMC article. Updated. Preprint.
Distinct Spatiotemporally Dynamic Wnt-Secreting Niches Regulate Proximal Airway Regeneration and Aging.
Aros CJ, Vijayaraj P, Pantoja CJ, Bisht B, Meneses LK, Sandlin JM, Tse JA, Chen MW, Purkayastha A, Shia DW, Sucre JMS, Rickabaugh TM, Vladar EK, Paul MK, Gomperts BN. Aros CJ, et al. Among authors: gomperts bn. Cell Stem Cell. 2020 Sep 3;27(3):413-429.e4. doi: 10.1016/j.stem.2020.06.019. Epub 2020 Jul 27. Cell Stem Cell. 2020. PMID: 32721381 Free PMC article.
Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response.
Purkayastha A, Sen C, Garcia G, Langerman J, Vijayaraj P, Shia DW, Meneses LK, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. Purkayastha A, et al. Among authors: gomperts bn. bioRxiv [Preprint]. 2020 Jul 29:2020.07.28.226092. doi: 10.1101/2020.07.28.226092. bioRxiv. 2020. PMID: 32766588 Free PMC article. Updated. Preprint.
Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response.
Purkayastha A, Sen C, Garcia G Jr, Langerman J, Shia DW, Meneses LK, Vijayaraj P, Durra A, Koloff CR, Freund DR, Chi J, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. Purkayastha A, et al. Among authors: gomperts bn. Cell Stem Cell. 2020 Dec 3;27(6):869-875.e4. doi: 10.1016/j.stem.2020.11.010. Epub 2020 Nov 17. Cell Stem Cell. 2020. PMID: 33259798 Free PMC article.
SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition.
Mullen PJ, Garcia G Jr, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. Mullen PJ, et al. Among authors: gomperts bn. Nat Commun. 2021 Mar 25;12(1):1876. doi: 10.1038/s41467-021-22166-4. Nat Commun. 2021. PMID: 33767183 Free PMC article.
158 results