Wolff KC - Search Results

1

Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.

Garcia G Jr, Sharma A, Ramaiah A, Sen C, Purkayastha A, Kohn DB, Parcells MS, Beck S, Kim H, Bakowski MA, Kirkpatrick MG, Riva L, Wolff KC, Han B, Yuen C, Ulmert D, Purbey PK, Scumpia P, Beutler N, Rogers TF, Chatterjee AK, Gabriel G, Bartenschlager R, Gomperts B, Svendsen CN, Betz UAK, Damoiseaux RD, Arumugaswami V. Garcia G Jr, et al. Among authors: wolff kc. Cell Rep. 2021 Apr 6;35(1):108940. doi: 10.1016/j.celrep.2021.108940. Epub 2021 Mar 18. Cell Rep. 2021. PMID: 33784499 Free PMC article.

2

Drug repurposing screens identify chemical entities for the development of COVID-19 interventions.

Bakowski MA, Beutler N, Wolff KC, Kirkpatrick MG, Chen E, Nguyen TH, Riva L, Shaabani N, Parren M, Ricketts J, Gupta AK, Pan K, Kuo P, Fuller M, Garcia E, Teijaro JR, Yang L, Sahoo D, Chi V, Huang E, Vargas N, Roberts AJ, Das S, Ghosh P, Woods AK, Joseph SB, Hull MV, Schultz PG, Burton DR, Chatterjee AK, McNamara CW, Rogers TF. Bakowski MA, et al. Among authors: wolff kc. Nat Commun. 2021 Jun 3;12(1):3309. doi: 10.1038/s41467-021-23328-0. Nat Commun. 2021. PMID: 34083527 Free PMC article.

3

Homogeneous high-throughput screening assays for HIV-1 integrase 3beta-processing and strand transfer activities.

Wang Y, Klock H, Yin H, Wolff K, Bieza K, Niswonger K, Matzen J, Gunderson D, Hale J, Lesley S, Kuhen K, Caldwell J, Brinker A. Wang Y, et al. J Biomol Screen. 2005 Aug;10(5):456-62. doi: 10.1177/1087057105275212. J Biomol Screen. 2005. PMID: 16093555

4

Dexamethasone inhibits respiratory syncytial virus-driven mucus production while increasing viral replication without altering antiviral interferon signaling.

McAllister CS, Ansaldi D, Growcott EJ, Zhong Y, Quackenbush D, Wolff KC, Chen Z, Tanaseichuk O, Lelais G, Barnes SW, Federe GC, Luna F, Walker JR, Zhou Y, Kuhen KL. McAllister CS, et al. Among authors: wolff kc. Virology. 2020 Jan 15;540:195-206. doi: 10.1016/j.virol.2019.10.007. Epub 2019 Oct 23. Virology. 2020. PMID: 31929001 Free article.

5

Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV).

Bonavia A, Franti M, Pusateri Keaney E, Kuhen K, Seepersaud M, Radetich B, Shao J, Honda A, Dewhurst J, Balabanis K, Monroe J, Wolff K, Osborne C, Lanieri L, Hoffmaster K, Amin J, Markovits J, Broome M, Skuba E, Cornella-Taracido I, Joberty G, Bouwmeester T, Hamann L, Tallarico JA, Tommasi R, Compton T, Bushell SM. Bonavia A, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6739-44. doi: 10.1073/pnas.1017142108. Epub 2011 Apr 18. Proc Natl Acad Sci U S A. 2011. PMID: 21502533 Free PMC article.

6

Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2.

Jiang T, Kuhen KL, Wolff K, Yin H, Bieza K, Caldwell J, Bursulaya B, Tuntland T, Zhang K, Karanewsky D, He Y. Jiang T, et al. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2109-12. doi: 10.1016/j.bmcl.2006.01.066. Epub 2006 Feb 7. Bioorg Med Chem Lett. 2006. PMID: 16464578

7

Just-in-time purification: an effective solution for cherry-picking and purifying active compounds from large legacy libraries.

Guintu C, Kwok M, Hanlon JJ, Spalding TA, Wolff K, Yin H, Kuhen K, Sasher K, Calvin P, Jiang S, Zhou Y, Isbell JJ. Guintu C, et al. J Biomol Screen. 2006 Dec;11(8):933-9. doi: 10.1177/1087057106294289. Epub 2006 Nov 7. J Biomol Screen. 2006. PMID: 17092919

8

Design, synthesis, and biological evaluations of novel quinolones as HIV-1 non-nucleoside reverse transcriptase inhibitors.

Ellis D, Kuhen KL, Anaclerio B, Wu B, Wolff K, Yin H, Bursulaya B, Caldwell J, Karanewsky D, He Y. Ellis D, et al. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4246-51. doi: 10.1016/j.bmcl.2006.05.073. Epub 2006 Jun 16. Bioorg Med Chem Lett. 2006. PMID: 16782337

9

Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I.

Jiang T, Kuhen KL, Wolff K, Yin H, Bieza K, Caldwell J, Bursulaya B, Wu TY, He Y. Jiang T, et al. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2105-8. doi: 10.1016/j.bmcl.2006.01.073. Epub 2006 Feb 9. Bioorg Med Chem Lett. 2006. PMID: 16480865

10

"UnPAKing" human immunodeficiency virus (HIV) replication: using small interfering RNA screening to identify novel cofactors and elucidate the role of group I PAKs in HIV infection.

Nguyen DG, Wolff KC, Yin H, Caldwell JS, Kuhen KL. Nguyen DG, et al. Among authors: wolff kc. J Virol. 2006 Jan;80(1):130-7. doi: 10.1128/JVI.80.1.130-137.2006. J Virol. 2006. PMID: 16352537 Free PMC article.

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