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Designed proteins assemble antibodies into modular nanocages.
Divine R, Dang HV, Ueda G, Fallas JA, Vulovic I, Sheffler W, Saini S, Zhao YT, Raj IX, Morawski PA, Jennewein MF, Homad LJ, Wan YH, Tooley MR, Seeger F, Etemadi A, Fahning ML, Lazarovits J, Roederer A, Walls AC, Stewart L, Mazloomi M, King NP, Campbell DJ, McGuire AT, Stamatatos L, Ruohola-Baker H, Mathieu J, Veesler D, Baker D. Divine R, et al. Among authors: baker d. Science. 2021 Apr 2;372(6537):eabd9994. doi: 10.1126/science.abd9994. Science. 2021. PMID: 33795432 Free PMC article.
Computational thermostabilization of an enzyme.
Korkegian A, Black ME, Baker D, Stoddard BL. Korkegian A, et al. Among authors: baker d. Science. 2005 May 6;308(5723):857-60. doi: 10.1126/science.1107387. Science. 2005. PMID: 15879217 Free PMC article.
Progress in modeling of protein structures and interactions.
Schueler-Furman O, Wang C, Bradley P, Misura K, Baker D. Schueler-Furman O, et al. Among authors: baker d. Science. 2005 Oct 28;310(5748):638-42. doi: 10.1126/science.1112160. Science. 2005. PMID: 16254179 Review.
A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila.
Yatsenko AS, Gray EE, Shcherbata HR, Patterson LB, Sood VD, Kucherenko MM, Baker D, Ruohola-Baker H. Yatsenko AS, et al. Among authors: baker d. J Biol Chem. 2007 May 18;282(20):15159-69. doi: 10.1074/jbc.M608800200. Epub 2007 Mar 12. J Biol Chem. 2007. PMID: 17355978 Free article.
De novo computational design of retro-aldol enzymes.
Jiang L, Althoff EA, Clemente FR, Doyle L, Röthlisberger D, Zanghellini A, Gallaher JL, Betker JL, Tanaka F, Barbas CF 3rd, Hilvert D, Houk KN, Stoddard BL, Baker D. Jiang L, et al. Among authors: baker d. Science. 2008 Mar 7;319(5868):1387-91. doi: 10.1126/science.1152692. Science. 2008. PMID: 18323453 Free PMC article.
5,661 results