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CD169/SIGLEC1 is expressed on circulating monocytes in COVID-19 and expression levels are associated with disease severity.
Doehn JM, Tabeling C, Biesen R, Saccomanno J, Madlung E, Pappe E, Gabriel F, Kurth F, Meisel C, Corman VM, Hanitsch LG, Treskatsch S, Heim K, Stegemann MS, Ruwwe-Glösenkamp C, Müller-Redetzky HC, Uhrig A, Somasundaram R, Spies C, von Bernuth H, Hofmann J, Drosten C, Suttorp N, Witzenrath M, Sander LE, Hübner RH. Doehn JM, et al. Among authors: heim k. Infection. 2021 Aug;49(4):757-762. doi: 10.1007/s15010-021-01606-9. Epub 2021 Apr 6. Infection. 2021. PMID: 33825125 Free PMC article.
Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load.
Schuch A, Salimi Alizei E, Heim K, Wieland D, Kiraithe MM, Kemming J, Llewellyn-Lacey S, Sogukpinar Ö, Ni Y, Urban S, Zimmermann P, Nassal M, Emmerich F, Price DA, Bengsch B, Luxenburger H, Neumann-Haefelin C, Hofmann M, Thimme R. Schuch A, et al. Among authors: heim k. Gut. 2019 May;68(5):905-915. doi: 10.1136/gutjnl-2018-316641. Epub 2019 Jan 8. Gut. 2019. PMID: 30622109 Free article.
MMP2/MMP9-mediated CD100 shedding is crucial for inducing intrahepatic anti-HBV CD8 T cell responses and HBV clearance.
Yang S, Wang L, Pan W, Bayer W, Thoens C, Heim K, Dittmer U, Timm J, Wang Q, Yu Q, Luo J, Liu Y, Hofmann M, Thimme R, Zhang X, Chen H, Wang H, Feng X, Yang X, Lu Y, Lu M, Yang D, Liu J. Yang S, et al. Among authors: heim k. J Hepatol. 2019 Oct;71(4):685-698. doi: 10.1016/j.jhep.2019.05.013. Epub 2019 Jun 5. J Hepatol. 2019. PMID: 31173811
TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection.
Heim K, Binder B, Sagar, Wieland D, Hensel N, Llewellyn-Lacey S, Gostick E, Price DA, Emmerich F, Vingerhoet H, Kraft ARM, Cornberg M, Boettler T, Neumann-Haefelin C, Zehn D, Bengsch B, Hofmann M, Thimme R. Heim K, et al. Gut. 2020 Oct 23;70(8):1550-60. doi: 10.1136/gutjnl-2020-322404. Online ahead of print. Gut. 2020. PMID: 33097558 Free PMC article.
Adaptive Subsets Limit the Anti-Tumoral NK-Cell Activity in Hepatocellular Carcinoma.
Rennert C, Tauber C, Fehrenbach P, Heim K, Bettinger D, Sogukpinar Ö, Schuch A, Zecher BF, Bengsch B, Lang SA, Bronsert P, Björkström NK, Fichtner-Feigl S, Schultheiss M, Thimme R, Hofmann M. Rennert C, et al. Among authors: heim k. Cells. 2021 Jun 2;10(6):1369. doi: 10.3390/cells10061369. Cells. 2021. PMID: 34199483 Free PMC article. Clinical Trial.
COVID-19 mRNA booster vaccine induces transient CD8+ T effector cell responses while conserving the memory pool for subsequent reactivation.
Reinscheid M, Luxenburger H, Karl V, Graeser A, Giese S, Ciminski K, Reeg DB, Oberhardt V, Roehlen N, Lang-Meli J, Heim K, Gross N, Baum C, Rieg S, Speer C, Emmerich F, Breisinger S, Steinmann D, Bengsch B, Boettler T, Kochs G, Schwemmle M, Thimme R, Neumann-Haefelin C, Hofmann M. Reinscheid M, et al. Among authors: heim k. Nat Commun. 2022 Aug 8;13(1):4631. doi: 10.1038/s41467-022-32324-x. Nat Commun. 2022. PMID: 35941157 Free PMC article.
Neoantigens as potential vaccines in hepatocellular carcinoma.
Repáraz D, Ruiz M, Llopiz D, Silva L, Vercher E, Aparicio B, Egea J, Tamayo-Uria I, Hervás-Stubbs S, García-Balduz J, Castro C, Iñarrairaegui M, Tagliamonte M, Mauriello A, Cavalluzzo B, Buonaguro L, Rohrer C, Heim K, Tauber C, Hofmann M, Thimme R, Sangro B, Sarobe P. Repáraz D, et al. Among authors: heim k. J Immunother Cancer. 2022 Feb;10(2):e003978. doi: 10.1136/jitc-2021-003978. J Immunother Cancer. 2022. PMID: 35193931 Free PMC article.
Somite development in the avian tail.
Draga M, Heim K, Batke R, Wegele M, Pröls F, Scaal M. Draga M, et al. Among authors: heim k. J Anat. 2019 Oct;235(4):716-724. doi: 10.1111/joa.13032. Epub 2019 Jun 21. J Anat. 2019. PMID: 31225912 Free PMC article.
Use of an Outbred Rat Hepacivirus Challenge Model for Design and Evaluation of Efficacy of Different Immunization Strategies for Hepatitis C Virus.
Atcheson E, Li W, Bliss CM, Chinnakannan S, Heim K, Sharpe H, Hutchings C, Dietrich I, Nguyen D, Kapoor A, Jarvis MA, Klenerman P, Barnes E, Simmonds P. Atcheson E, et al. Among authors: heim k. Hepatology. 2020 Mar;71(3):794-807. doi: 10.1002/hep.30894. Epub 2019 Oct 11. Hepatology. 2020. PMID: 31400152 Free PMC article.
200 results