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RTEL-1 enforces meiotic crossover interference and homeostasis.
Youds JL, Mets DG, McIlwraith MJ, Martin JS, Ward JD, ONeil NJ, Rose AM, West SC, Meyer BJ, Boulton SJ. Youds JL, et al. Among authors: west sc. Science. 2010 Mar 5;327(5970):1254-8. doi: 10.1126/science.1183112. Science. 2010. PMID: 20203049 Free PMC article.
Keeping homologous recombination in check.
Fugger K, West SC. Fugger K, et al. Among authors: west sc. Cell Res. 2016 Apr;26(4):397-8. doi: 10.1038/cr.2016.25. Epub 2016 Feb 23. Cell Res. 2016. PMID: 26902288 Free PMC article.
Repeat expansions confer WRN dependence in microsatellite-unstable cancers.
van Wietmarschen N, Sridharan S, Nathan WJ, Tubbs A, Chan EM, Callen E, Wu W, Belinky F, Tripathi V, Wong N, Foster K, Noorbakhsh J, Garimella K, Cruz-Migoni A, Sommers JA, Huang Y, Borah AA, Smith JT, Kalfon J, Kesten N, Fugger K, Walker RL, Dolzhenko E, Eberle MA, Hayward BE, Usdin K, Freudenreich CH, Brosh RM Jr, West SC, McHugh PJ, Meltzer PS, Bass AJ, Nussenzweig A. van Wietmarschen N, et al. Among authors: west sc. Nature. 2020 Oct;586(7828):292-298. doi: 10.1038/s41586-020-2769-8. Epub 2020 Sep 30. Nature. 2020. PMID: 32999459 Free PMC article.
MutSβ Stimulates Holliday Junction Resolution by the SMX Complex.
Young SJ, Sebald M, Shah Punatar R, Larin M, Masino L, Rodrigo-Brenni MC, Liang CC, West SC. Young SJ, et al. Among authors: west sc. Cell Rep. 2020 Oct 20;33(3):108289. doi: 10.1016/j.celrep.2020.108289. Cell Rep. 2020. PMID: 33086055 Free article.
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, Schneider-Luftman D, Herbert E, Stamp G, Brough R, Pettitt S, Lord CJ, West SC, Ahel I, Ahel D, Chapman JR, Deindl S, Boulton SJ. Hewitt G, et al. Among authors: west sc. Mol Cell. 2021 Feb 18;81(4):767-783.e11. doi: 10.1016/j.molcel.2020.12.006. Epub 2020 Dec 16. Mol Cell. 2021. PMID: 33333017 Free PMC article.
288 results