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Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung.
Ogongo P, Tezera LB, Ardain A, Nhamoyebonde S, Ramsuran D, Singh A, Ng'oepe A, Karim F, Naidoo T, Khan K, Dullabh KJ, Fehlings M, Lee BH, Nardin A, Lindestam Arlehamn CS, Sette A, Behar SM, Steyn AJ, Madansein R, Kløverpris HN, Elkington PT, Leslie A. Ogongo P, et al. Among authors: madansein r. J Clin Invest. 2021 May 17;131(10):e142014. doi: 10.1172/JCI142014. J Clin Invest. 2021. PMID: 33848273 Free PMC article. Clinical Trial.
Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection.
Nunes-Alves C, Booty MG, Carpenter SM, Rothchild AC, Martin CJ, Desjardins D, Steblenko K, Kløverpris HN, Madansein R, Ramsuran D, Leslie A, Correia-Neves M, Behar SM. Nunes-Alves C, et al. Among authors: madansein r. PLoS Pathog. 2015 May 6;11(5):e1004849. doi: 10.1371/journal.ppat.1004849. eCollection 2015 May. PLoS Pathog. 2015. PMID: 25945999 Free PMC article.
Towards host-directed therapies for tuberculosis.
Zumla A, Maeurer M; Host-Directed Therapies Network; Chakaya J, Hoelscher M, Ntoumi F, Rustomjee R, Vilaplana C, Yeboah-Manu D, Rasolof V, Munderi P, Singh N, Aklillu E, Padayatchi N, Macete E, Kapata N, Mulenga M, Kibiki G, Mfinanga S, Nyirenda T, Maboko L, Garcia-Basteiro A, Rakotosamimanana N, Bates M, Mwaba P, Reither K, Gagneux S, Edwards S, Mfinanga E, Abdulla S, Cardona PJ, Russell JB, Gant V, Noursadeghi M, Elkington P, Bonnet M, Menendez C, Dieye TN, Diarra B, Maiga A, Aseffa A, Parida S, Wejse C, Petersen E, Kaleebu P, Oliver M, Craig G, Corrah T, Tientcheu L, Antonio M, Rao M, McHugh TD, Sheikh A, Ippolito G, Ramjee G, Kaufmann SH, Churchyard G, Steyn A, Grobusch M, Sanne I, Martinson N, Madansein R, Wilkinson RJ, Mayosi B, Schito M, Wallis RS. Zumla A, et al. Among authors: madansein r. Nat Rev Drug Discov. 2015 Aug;14(8):511-2. doi: 10.1038/nrd4696. Epub 2015 Jul 17. Nat Rev Drug Discov. 2015. PMID: 26184493 Free article.
Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.
Reddy VP, Chinta KC, Saini V, Glasgow JN, Hull TD, Traylor A, Rey-Stolle F, Soares MP, Madansein R, Rahman MA, Barbas C, Nargan K, Naidoo T, Ramdial PK, George JF, Agarwal A, Steyn AJC. Reddy VP, et al. Among authors: madansein r. Front Immunol. 2018 May 3;9:860. doi: 10.3389/fimmu.2018.00860. eCollection 2018. Front Immunol. 2018. PMID: 29774023 Free PMC article.
Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis.
Chinta KC, Rahman MA, Saini V, Glasgow JN, Reddy VP, Lever JM, Nhamoyebonde S, Leslie A, Wells RM, Traylor A, Madansein R, Siegal GP, Antony VB, Deshane J, Wells G, Nargan K, George JF, Ramdial PK, Agarwal A, Steyn AJC. Chinta KC, et al. Among authors: madansein r. Cell Rep. 2018 Nov 13;25(7):1938-1952.e5. doi: 10.1016/j.celrep.2018.10.073. Cell Rep. 2018. PMID: 30428359 Free PMC article.
Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.
Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA. Ardain A, et al. Among authors: madansein r. Nature. 2019 Jun;570(7762):528-532. doi: 10.1038/s41586-019-1276-2. Epub 2019 Jun 5. Nature. 2019. PMID: 31168092 Free PMC article.
TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis.
Wong EB, Gold MC, Meermeier EW, Xulu BZ, Khuzwayo S, Sullivan ZA, Mahyari E, Rogers Z, Kløverpris H, Sharma PK, Worley AH, Lalloo U, Baijnath P, Ambaram A, Naidoo L, Suleman M, Madansein R, McLaren JE, Ladell K, Miners KL, Price DA, Behar SM, Nielsen M, Kasprowicz VO, Leslie A, Bishai WR, Ndung'u T, Lewinsohn DM. Wong EB, et al. Among authors: madansein r. Commun Biol. 2019 Jun 5;2:203. doi: 10.1038/s42003-019-0442-2. eCollection 2019. Commun Biol. 2019. PMID: 31231693 Free PMC article.
Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.
Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, Ulland TK, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA. Ardain A, et al. Among authors: madansein r. Nature. 2019 Aug;572(7768):E10. doi: 10.1038/s41586-019-1458-y. Nature. 2019. PMID: 31337923
Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis.
Chinta KC, Rahman MA, Saini V, Glasgow JN, Reddy VP, Lever JM, Nhamoyebonde S, Leslie A, Wells RM, Traylor A, Madansein R, Siegal GP, Antony VB, Deshane J, Wells G, Nargan K, George JF, Ramdial PK, Agarwal A, Steyn AJC. Chinta KC, et al. Among authors: madansein r. Cell Rep. 2019 Sep 17;28(12):3286. doi: 10.1016/j.celrep.2019.08.081. Cell Rep. 2019. PMID: 31533049 Free PMC article. No abstract available.
39 results