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AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Maiani E, Milletti G, Nazio F, Holdgaard SG, Bartkova J, Rizza S, Cianfanelli V, Lorente M, Simoneschi D, Di Marco M, D'Acunzo P, Di Leo L, Rasmussen R, Montagna C, Raciti M, De Stefanis C, Gabicagogeascoa E, Rona G, Salvador N, Pupo E, Merchut-Maya JM, Daniel CJ, Carinci M, Cesarini V, O'sullivan A, Jeong YT, Bordi M, Russo F, Campello S, Gallo A, Filomeni G, Lanzetti L, Sears RC, Hamerlik P, Bartolazzi A, Hynds RE, Pearce DR, Swanton C, Pagano M, Velasco G, Papaleo E, De Zio D, Maya-Mendoza A, Locatelli F, Bartek J, Cecconi F. Maiani E, et al. Among authors: cecconi f. Nature. 2021 Apr;592(7856):799-803. doi: 10.1038/s41586-021-03422-5. Epub 2021 Apr 14. Nature. 2021. PMID: 33854232 Free PMC article.
Ambra1 regulates autophagy and development of the nervous system.
Fimia GM, Stoykova A, Romagnoli A, Giunta L, Di Bartolomeo S, Nardacci R, Corazzari M, Fuoco C, Ucar A, Schwartz P, Gruss P, Piacentini M, Chowdhury K, Cecconi F. Fimia GM, et al. Among authors: cecconi f. Nature. 2007 Jun 28;447(7148):1121-5. doi: 10.1038/nature05925. Epub 2007 Jun 24. Nature. 2007. PMID: 17589504
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells.
Salazar M, Carracedo A, Salanueva IJ, Hernández-Tiedra S, Lorente M, Egia A, Vázquez P, Blázquez C, Torres S, García S, Nowak J, Fimia GM, Piacentini M, Cecconi F, Pandolfi PP, González-Feria L, Iovanna JL, Guzmán M, Boya P, Velasco G. Salazar M, et al. Among authors: cecconi f. J Clin Invest. 2009 May;119(5):1359-72. doi: 10.1172/jci37948. J Clin Invest. 2009. PMID: 19425170 Free PMC article.
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy.
Di Bartolomeo S, Corazzari M, Nazio F, Oliverio S, Lisi G, Antonioli M, Pagliarini V, Matteoni S, Fuoco C, Giunta L, D'Amelio M, Nardacci R, Romagnoli A, Piacentini M, Cecconi F, Fimia GM. Di Bartolomeo S, et al. Among authors: cecconi f. J Cell Biol. 2010 Oct 4;191(1):155-68. doi: 10.1083/jcb.201002100. J Cell Biol. 2010. PMID: 20921139 Free PMC article.
The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage.
De Zio D, Bordi M, Tino E, Lanzuolo C, Ferraro E, Mora E, Ciccosanti F, Fimia GM, Orlando V, Cecconi F. De Zio D, et al. Among authors: cecconi f. Cell Death Differ. 2011 Mar;18(3):516-27. doi: 10.1038/cdd.2010.125. Epub 2010 Oct 22. Cell Death Differ. 2011. PMID: 20966962 Free PMC article.
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease.
D'Amelio M, Cavallucci V, Middei S, Marchetti C, Pacioni S, Ferri A, Diamantini A, De Zio D, Carrara P, Battistini L, Moreno S, Bacci A, Ammassari-Teule M, Marie H, Cecconi F. D'Amelio M, et al. Among authors: cecconi f. Nat Neurosci. 2011 Jan;14(1):69-76. doi: 10.1038/nn.2709. Epub 2010 Dec 12. Nat Neurosci. 2011. PMID: 21151119
Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy.
Strappazzon F, Vietri-Rudan M, Campello S, Nazio F, Florenzano F, Fimia GM, Piacentini M, Levine B, Cecconi F. Strappazzon F, et al. Among authors: cecconi f. EMBO J. 2011 Apr 6;30(7):1195-208. doi: 10.1038/emboj.2011.49. Epub 2011 Feb 25. EMBO J. 2011. PMID: 21358617 Free PMC article.
312 results