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Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.
Gangoso E, Southgate B, Bradley L, Rus S, Galvez-Cancino F, McGivern N, Güç E, Kapourani CA, Byron A, Ferguson KM, Alfazema N, Morrison G, Grant V, Blin C, Sou I, Marques-Torrejon MA, Conde L, Parrinello S, Herrero J, Beck S, Brandner S, Brennan PM, Bertone P, Pollard JW, Quezada SA, Sproul D, Frame MC, Serrels A, Pollard SM. Gangoso E, et al. Among authors: parrinello s. Cell. 2021 Apr 29;184(9):2454-2470.e26. doi: 10.1016/j.cell.2021.03.023. Epub 2021 Apr 14. Cell. 2021. PMID: 33857425 Free PMC article.
EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells.
Krusche B, Ottone C, Clements MP, Johnstone ER, Goetsch K, Lieven H, Mota SG, Singh P, Khadayate S, Ashraf A, Davies T, Pollard SM, De Paola V, Roncaroli F, Martinez-Torrecuadrada J, Bertone P, Parrinello S. Krusche B, et al. Among authors: parrinello s. Elife. 2016 Jun 28;5:e14845. doi: 10.7554/eLife.14845. Elife. 2016. PMID: 27350048 Free PMC article.
The white matter is a pro-differentiative niche for glioblastoma.
Brooks LJ, Clements MP, Burden JJ, Kocher D, Richards L, Devesa SC, Zakka L, Woodberry M, Ellis M, Jaunmuktane Z, Brandner S, Morrison G, Pollard SM, Dirks PB, Marguerat S, Parrinello S. Brooks LJ, et al. Among authors: parrinello s. Nat Commun. 2021 Apr 12;12(1):2184. doi: 10.1038/s41467-021-22225-w. Nat Commun. 2021. PMID: 33846316 Free PMC article.
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells.
Marqués-Torrejón MÁ, Williams CAC, Southgate B, Alfazema N, Clements MP, Garcia-Diaz C, Blin C, Arranz-Emparan N, Fraser J, Gammoh N, Parrinello S, Pollard SM. Marqués-Torrejón MÁ, et al. Among authors: parrinello s. Nat Commun. 2021 May 10;12(1):2594. doi: 10.1038/s41467-021-22813-w. Nat Commun. 2021. PMID: 33972529 Free PMC article.
Author Correction: The white matter is a pro-differentiative niche for glioblastoma.
Brooks LJ, Clements MP, Burden JJ, Kocher D, Richards L, Devesa SC, Zakka L, Woodberry M, Ellis M, Jaunmuktane Z, Brandner S, Morrison G, Pollard SM, Dirks PB, Marguerat S, Parrinello S. Brooks LJ, et al. Among authors: parrinello s. Nat Commun. 2022 Apr 14;13(1):2163. doi: 10.1038/s41467-022-29916-y. Nat Commun. 2022. PMID: 35422055 Free PMC article. No abstract available.
Injury programs shape glioblastoma.
Brooks LJ, Simpson Ragdale H, Hill CS, Clements M, Parrinello S. Brooks LJ, et al. Among authors: parrinello s. Trends Neurosci. 2022 Nov;45(11):865-876. doi: 10.1016/j.tins.2022.08.006. Epub 2022 Sep 9. Trends Neurosci. 2022. PMID: 36089406 Free article. Review.
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin.
Garcia-Diaz C, Pöysti A, Mereu E, Clements MP, Brooks LJ, Galvez-Cancino F, Castillo SP, Tang W, Beattie G, Courtot L, Ruiz S, Roncaroli F, Yuan Y, Marguerat S, Quezada SA, Heyn H, Parrinello S. Garcia-Diaz C, et al. Among authors: parrinello s. Cell Rep. 2023 May 30;42(5):112472. doi: 10.1016/j.celrep.2023.112472. Epub 2023 May 5. Cell Rep. 2023. PMID: 37149862 Free article.
Vascular regulation of glioma stem-like cells: a balancing act.
Brooks LJ, Parrinello S. Brooks LJ, et al. Among authors: parrinello s. Curr Opin Neurobiol. 2017 Dec;47:8-15. doi: 10.1016/j.conb.2017.06.008. Epub 2017 Jul 18. Curr Opin Neurobiol. 2017. PMID: 28732340 Free article. Review.
39 results