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Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis, prognosis and drug target discovery.
Li Y, Hou G, Zhou H, Wang Y, Tun HM, Zhu A, Zhao J, Xiao F, Lin S, Liu D, Zhou D, Mai L, Zhang L, Zhang Z, Kuang L, Guan J, Chen Q, Wen L, Zhang Y, Zhuo J, Li F, Zhuang Z, Chen Z, Luo L, Liu D, Chen C, Gan M, Zhong N, Zhao J, Ren Y, Xu Y. Li Y, et al. Among authors: chen z, chen q, chen c. Signal Transduct Target Ther. 2021 Apr 15;6(1):155. doi: 10.1038/s41392-021-00508-4. Signal Transduct Target Ther. 2021. PMID: 33859163 Free PMC article.
Kinetics of viral load and antibody response in relation to COVID-19 severity.
Wang Y, Zhang L, Sang L, Ye F, Ruan S, Zhong B, Song T, Alshukairi AN, Chen R, Zhang Z, Gan M, Zhu A, Huang Y, Luo L, Mok CKP, Al Gethamy MM, Tan H, Li Z, Huang X, Li F, Sun J, Zhang Y, Wen L, Li Y, Chen Z, Zhuang Z, Zhuo J, Chen C, Kuang L, Wang J, Lv H, Jiang Y, Li M, Lin Y, Deng Y, Tang L, Liang J, Huang J, Perlman S, Zhong N, Zhao J, Malik Peiris JS, Li Y, Zhao J. Wang Y, et al. Among authors: chen z, chen r, chen c. J Clin Invest. 2020 Oct 1;130(10):5235-5244. doi: 10.1172/JCI138759. J Clin Invest. 2020. PMID: 32634129 Free PMC article. Clinical Trial.
Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment.
Sun J, Zhuang Z, Zheng J, Li K, Wong RL, Liu D, Huang J, He J, Zhu A, Zhao J, Li X, Xi Y, Chen R, Alshukairi AN, Chen Z, Zhang Z, Chen C, Huang X, Li F, Lai X, Chen D, Wen L, Zhuo J, Zhang Y, Wang Y, Huang S, Dai J, Shi Y, Zheng K, Leidinger MR, Chen J, Li Y, Zhong N, Meyerholz DK, McCray PB Jr, Perlman S, Zhao J. Sun J, et al. Among authors: chen z, chen j, chen r, chen c, chen d. Cell. 2020 Aug 6;182(3):734-743.e5. doi: 10.1016/j.cell.2020.06.010. Epub 2020 Jun 10. Cell. 2020. PMID: 32643603 Free PMC article.
Age-related seroprevalence trajectories of seasonal coronaviruses in children including neonates in Guangzhou, China.
Luo Y, Lv H, Zhao S, Sun Y, Liu C, Chen C, Liang W, Kwok KO, Teo QW, So RT, Lin Y, Deng Y, Li B, Dai Z, Zhu J, Zhang D, Fernando J, Wu NC, Tun HM, Bruzzone R, Mok CK, Mu X. Luo Y, et al. Among authors: chen c. Int J Infect Dis. 2023 Feb;127:26-32. doi: 10.1016/j.ijid.2022.11.044. Epub 2022 Dec 5. Int J Infect Dis. 2023. PMID: 36481488 Free PMC article.
Mouse models susceptible to HCoV-229E and HCoV-NL63 and cross protection from challenge with SARS-CoV-2.
Liu D, Chen C, Chen D, Zhu A, Li F, Zhuang Z, Mok CKP, Dai J, Li X, Jin Y, Chen Z, Sun J, Wang Y, Li Y, Zhang Y, Wen L, Zhang Z, Zhuo J, Wang J, Ran W, Wang D, Zhang S, Tang Y, Li S, Lai X, Wei P, Yuan J, Chen F, Huang S, Sun F, Qian Z, Tan W, Zhao J, Peiris M, Zhao J. Liu D, et al. Among authors: chen z, chen c, chen d, chen f. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2202820120. doi: 10.1073/pnas.2202820120. Epub 2023 Jan 18. Proc Natl Acad Sci U S A. 2023. PMID: 36652473 Free PMC article.
Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines.
Peng Y, Zhang L, Mok CKP, Ching JYL, Zhao S, Wong MKL, Zhu J, Chen C, Wang S, Yan S, Qin B, Liu Y, Zhang X, Cheung CP, Cheong PK, Ip KL, Fung ACH, Wong KKY, Hui DSC, Chan FKL, Ng SC, Tun HM. Peng Y, et al. Among authors: chen c. Signal Transduct Target Ther. 2023 Sep 25;8(1):373. doi: 10.1038/s41392-023-01629-8. Signal Transduct Target Ther. 2023. PMID: 37743379 Free PMC article.
Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID-19 vaccines in Hong Kong.
Mok CKP, Cohen CA, Cheng SMS, Chen C, Kwok KO, Yiu K, Chan TO, Bull M, Ling KC, Dai Z, Ng SS, Lui GC, Wu C, Amarasinghe GK, Leung DW, Wong SYS, Valkenburg SA, Peiris M, Hui DS. Mok CKP, et al. Among authors: chen c. Respirology. 2022 Apr;27(4):301-310. doi: 10.1111/resp.14191. Epub 2021 Nov 24. Respirology. 2022. PMID: 34820940 Free PMC article.
SARS-CoV-2 Omicron variant BA.2 neutralisation in sera of people with Comirnaty or CoronaVac vaccination, infection or breakthrough infection, Hong Kong, 2020 to 2022.
Cheng SM, Mok CKP, Chan KC, Ng SS, Lam BH, Luk LL, Ko FW, Chen C, Yiu K, Li JK, Chan KK, Tsang LC, Poon LL, Hui DS, Peiris M. Cheng SM, et al. Among authors: chen c. Euro Surveill. 2022 May;27(18):2200178. doi: 10.2807/1560-7917.ES.2022.27.18.2200178. Euro Surveill. 2022. PMID: 35514306 Free PMC article.
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