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SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Rosa A, Pye VE, Graham C, Muir L, Seow J, Ng KW, Cook NJ, Rees-Spear C, Parker E, Dos Santos MS, Rosadas C, Susana A, Rhys H, Nans A, Masino L, Roustan C, Christodoulou E, Ulferts R, Wrobel AG, Short CE, Fertleman M, Sanders RW, Heaney J, Spyer M, Kjær S, Riddell A, Malim MH, Beale R, MacRae JI, Taylor GP, Nastouli E, van Gils MJ, Rosenthal PB, Pizzato M, McClure MO, Tedder RS, Kassiotis G, McCoy LE, Doores KJ, Cherepanov P. Rosa A, et al. Among authors: christodoulou e. Sci Adv. 2021 May 28;7(22):eabg7607. doi: 10.1126/sciadv.abg7607. Print 2021 May. Sci Adv. 2021. PMID: 33888467 Free PMC article.
SARS-CoV-2 recruits a haem metabolite to evade antibody immunity.
Rosa A, Pye VE, Graham C, Muir L, Seow J, Ng KW, Cook NJ, Rees-Spear C, Parker E, Dos Santos MS, Rosadas C, Susana A, Rhys H, Nans A, Masino L, Roustan C, Christodoulou E, Ulferts R, Wrobel A, Short CE, Fertleman M, Sanders RW, Heaney J, Spyer M, Kjær S, Riddell A, Malim MH, Beale R, MacRae JI, Taylor GP, Nastouli E, van Gils MJ, Rosenthal PB, Pizzato M, McClure MO, Tedder RS, Kassiotis G, McCoy LE, Doores KJ, Cherepanov P. Rosa A, et al. Among authors: christodoulou e. medRxiv [Preprint]. 2021 Jan 26:2021.01.21.21249203. doi: 10.1101/2021.01.21.21249203. medRxiv. 2021. PMID: 33532784 Free PMC article. Updated. Preprint.
Structural basis of substrate discrimination and integrin binding by autotaxin.
Hausmann J, Kamtekar S, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HM, van Meeteren LA, Houben AJ, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, Kasiem M, Harlos K, Kooi CW, Smyth SS, Ovaa H, Bollen M, Morris AJ, Moolenaar WH, Perrakis A. Hausmann J, et al. Among authors: christodoulou e. Nat Struct Mol Biol. 2011 Feb;18(2):198-204. doi: 10.1038/nsmb.1980. Epub 2011 Jan 16. Nat Struct Mol Biol. 2011. PMID: 21240271 Free PMC article.
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.
van Meeteren LA, Ruurs P, Christodoulou E, Goding JW, Takakusa H, Kikuchi K, Perrakis A, Nagano T, Moolenaar WH. van Meeteren LA, et al. Among authors: christodoulou e. J Biol Chem. 2005 Jun 3;280(22):21155-61. doi: 10.1074/jbc.M413183200. Epub 2005 Mar 15. J Biol Chem. 2005. PMID: 15769751 Free article.
Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein.
Hausmann J, Christodoulou E, Kasiem M, De Marco V, van Meeteren LA, Moolenaar WH, Axford D, Owen RL, Evans G, Perrakis A. Hausmann J, et al. Among authors: christodoulou e. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):1130-5. doi: 10.1107/S1744309110032938. Epub 2010 Aug 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20823545 Free PMC article.
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.
Heidebrecht T, Christodoulou E, Chalmers MJ, Jan S, Ter Riet B, Grover RK, Joosten RP, Littler D, van Luenen H, Griffin PR, Wentworth P Jr, Borst P, Perrakis A. Heidebrecht T, et al. Among authors: christodoulou e. Nucleic Acids Res. 2011 Jul;39(13):5715-28. doi: 10.1093/nar/gkr125. Epub 2011 Mar 16. Nucleic Acids Res. 2011. PMID: 21415010 Free PMC article.
Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases.
Luna-Vargas MP, Christodoulou E, Alfieri A, van Dijk WJ, Stadnik M, Hibbert RG, Sahtoe DD, Clerici M, Marco VD, Littler D, Celie PH, Sixma TK, Perrakis A. Luna-Vargas MP, et al. Among authors: christodoulou e. J Struct Biol. 2011 Aug;175(2):113-9. doi: 10.1016/j.jsb.2011.03.017. Epub 2011 Mar 29. J Struct Biol. 2011. PMID: 21453775
Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing.
De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A. De Marco V, et al. Among authors: christodoulou e. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19807-12. doi: 10.1073/pnas.0905281106. Epub 2009 Nov 11. Proc Natl Acad Sci U S A. 2009. PMID: 19906994 Free PMC article.
203 results