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Quality control of mislocalized and orphan proteins.
Exp Cell Res. 2021 Jun 15;403(2):112617. doi: 10.1016/j.yexcr.2021.112617. Epub 2021 Apr 28.
Exp Cell Res. 2021.
PMID: 33930402
Free article.
Review.
A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration.
Coelho JPL, Stahl M, Bloemeke N, Meighen-Berger K, Alvira CP, Zhang ZR, Sieber SA, Feige MJ.
Coelho JPL, et al.
Nat Commun. 2019 Feb 8;10(1):672. doi: 10.1038/s41467-019-08632-0.
Nat Commun. 2019.
PMID: 30737405
Free PMC article.
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Publisher Correction: A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration.
Coelho JPL, Stahl M, Bloemeke N, Meighen-Berger K, Alvira CP, Zhang ZR, Sieber SA, Feige MJ.
Coelho JPL, et al.
Nat Commun. 2019 Apr 18;10(1):1908. doi: 10.1038/s41467-019-09912-5.
Nat Commun. 2019.
PMID: 31000714
Free PMC article.
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In case of stress, hold tight: phosphorylation switches PDI from an oxidoreductase to a holdase, tuning ER proteostasis.
Coelho JPL, Feige MJ.
Coelho JPL, et al.
EMBO J. 2020 May 18;39(10):e104880. doi: 10.15252/embj.2020104880. Epub 2020 Apr 2.
EMBO J. 2020.
PMID: 32239769
Free PMC article.
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The human signal peptidase complex acts as a quality control enzyme for membrane proteins.
Zanotti A, Coelho JPL, Kaylani D, Singh G, Tauber M, Hitzenberger M, Avci D, Zacharias M, Russell RB, Lemberg MK, Feige MJ.
Zanotti A, et al. Among authors: coelho jpl.
Science. 2022 Dec 2;378(6623):996-1000. doi: 10.1126/science.abo5672. Epub 2022 Dec 1.
Science. 2022.
PMID: 36454823
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Intramembrane client recognition potentiates the chaperone functions of calnexin.
Bloemeke N, Meighen-Berger K, Hitzenberger M, Bach NC, Parr M, Coelho JP, Frishman D, Zacharias M, Sieber SA, Feige MJ.
Bloemeke N, et al.
EMBO J. 2022 Dec 15;41(24):e110959. doi: 10.15252/embj.2022110959. Epub 2022 Oct 31.
EMBO J. 2022.
PMID: 36314723
Free PMC article.
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A 'NAC' for targeting proteins to the ER.
Coelho JPL, Shao S.
Coelho JPL, et al.
Trends Biochem Sci. 2022 Sep;47(9):730-731. doi: 10.1016/j.tibs.2022.04.007. Epub 2022 Apr 29.
Trends Biochem Sci. 2022.
PMID: 35501234
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The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center.
Coelho JPL, Yip MCJ, Oltion K, Taunton J, Shao S.
Coelho JPL, et al.
Nat Chem Biol. 2024 Jan 3. doi: 10.1038/s41589-023-01521-0. Online ahead of print.
Nat Chem Biol. 2024.
PMID: 38172604
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