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Protein structure-based gene expression signatures.
Rahman R, Zatorski N, Hansen J, Xiong Y, van Hasselt JGC, Sobie EA, Birtwistle MR, Azeloglu EU, Iyengar R, Schlessinger A. Rahman R, et al. Among authors: van hasselt jgc. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2014866118. doi: 10.1073/pnas.2014866118. Proc Natl Acad Sci U S A. 2021. PMID: 33941686 Free PMC article.
Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity.
Calizo RC, Bhattacharya S, van Hasselt JGC, Wei C, Wong JS, Wiener RJ, Ge X, Wong NJ, Lee JJ, Cuttitta CM, Jayaraman G, Au VH, Janssen W, Liu T, Li H, Salem F, Jaimes EA, Murphy B, Campbell KN, Azeloglu EU. Calizo RC, et al. Among authors: van hasselt jgc. Nat Commun. 2019 May 3;10(1):2061. doi: 10.1038/s41467-019-09936-x. Nat Commun. 2019. PMID: 31053734 Free PMC article.
Towards personalized treatment of pain using a quantitative systems pharmacology approach.
Goulooze SC, Krekels EHJ, van Dijk M, Tibboel D, van der Graaf PH, Hankemeier T, Knibbe CAJ, van Hasselt JGC. Goulooze SC, et al. Among authors: van der graaf ph, van dijk m, van hasselt jgc. Eur J Pharm Sci. 2017 Nov 15;109S:S32-S38. doi: 10.1016/j.ejps.2017.05.027. Epub 2017 May 12. Eur J Pharm Sci. 2017. PMID: 28506867 Free article. Review.
Design principles of collateral sensitivity-based dosing strategies.
Aulin LBS, Liakopoulos A, van der Graaf PH, Rozen DE, van Hasselt JGC. Aulin LBS, et al. Among authors: van der graaf ph, van hasselt jgc. Nat Commun. 2021 Sep 28;12(1):5691. doi: 10.1038/s41467-021-25927-3. Nat Commun. 2021. PMID: 34584086 Free PMC article.
110 results