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Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma.
Olson DJ, Eroglu Z, Brockstein B, Poklepovic AS, Bajaj M, Babu S, Hallmeyer S, Velasco M, Lutzky J, Higgs E, Bao R, Carll TC, Labadie B, Krausz T, Zha Y, Karrison T, Sondak VK, Gajewski TF, Khushalani NI, Luke JJ. Olson DJ, et al. Among authors: higgs e. J Clin Oncol. 2021 Aug 20;39(24):2647-2655. doi: 10.1200/JCO.21.00079. Epub 2021 May 4. J Clin Oncol. 2021. PMID: 33945288 Free PMC article. Clinical Trial.
STING pathway agonism as a cancer therapeutic.
Flood BA, Higgs EF, Li S, Luke JJ, Gajewski TF. Flood BA, et al. Immunol Rev. 2019 Jul;290(1):24-38. doi: 10.1111/imr.12765. Immunol Rev. 2019. PMID: 31355488 Free PMC article. Review.
Immunotherapy with a sting.
Gajewski TF, Higgs EF. Gajewski TF, et al. Science. 2020 Aug 21;369(6506):921-922. doi: 10.1126/science.abc6622. Science. 2020. PMID: 32820113 No abstract available.
COVIDOSE: A Phase II Clinical Trial of Low-Dose Tocilizumab in the Treatment of Noncritical COVID-19 Pneumonia.
Strohbehn GW, Heiss BL, Rouhani SJ, Trujillo JA, Yu J, Kacew AJ, Higgs EF, Bloodworth JC, Cabanov A, Wright RC, Koziol AK, Weiss A, Danahey K, Karrison TG, Edens CC, Bauer Ventura I, Pettit NN, Patel BK, Pisano J, Strek ME, Gajewski TF, Ratain MJ, Reid PD. Strohbehn GW, et al. Among authors: higgs ef. Clin Pharmacol Ther. 2021 Mar;109(3):688-696. doi: 10.1002/cpt.2117. Epub 2020 Dec 10. Clin Pharmacol Ther. 2021. PMID: 33210302 Free PMC article. Clinical Trial.
Severe COVID-19 infection is associated with aberrant cytokine production by infected lung epithelial cells rather than by systemic immune dysfunction.
Rouhani SJ, Trujillo JA, Pyzer AR, Yu J, Fessler J, Cabanov A, Higgs EF, Cron KR, Zha Y, Lu Y, Bloodworth JC, Abasiyanik MF, Okrah S, Flood BA, Hatogai K, Leung MY, Pezeshk A, Kozloff L, Reschke R, Strohbehn GW, Chervin CS, Kumar M, Schrantz S, Madariaga ML, Beavis KG, Yeo KJ, Sweis RF, Segal J, Tay S, Izumchenko E, Mueller J, Chen LS, Gajewski TF. Rouhani SJ, et al. Among authors: higgs ef. Res Sq [Preprint]. 2021 Nov 24:rs.3.rs-1083825. doi: 10.21203/rs.3.rs-1083825/v1. Res Sq. 2021. PMID: 34845442 Free PMC article. Preprint.
170 results